Formulation and characterization of polyherbal phytosomal nanoparticles

This research focuses on the formulating and characterizating of polyherbal phytosomal nanoparticles with Methotrexate, (MTX) and polyherbal extracts for enhanced cancer therapy. Nanoparticles were synthesized using soya lecithin and evaluated for particle size (310 nm), zeta potential (-18.3 mV), encapsulation efficiency (79.71%), FTIR compatibility, and stability. Stability studies demonstrated the formulation's robustness at room temperature for three months. The results underscore the promise of phytosomal nanoparticles in optimizing herbal-based therapeutic strategies, highlighting their potential for enhanced cancer therapy.

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Publication Details

Journal
International Journal of Pharmacognosy and Life Science
Published
2025-01-01
DOI
https://doi.org/10.33545/27072827.2025.v6.i1a.141
Primary Topic
Toxin Mechanisms and Immunotoxins
Type
article
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article

Formulation and characterization of polyherbal phytosomal nanoparticles

Swati J. Patil, S.P. Pawar
International Journal of Pharmacognosy and Life Science
Toxin Mechanisms and Immunotoxins
article

Formulation and characterization of polyherbal phytosomal nanoparticles

Swati J. Patil, S.P. Pawar
article en

Abstract

This research focuses on the formulating and characterizating of polyherbal phytosomal nanoparticles with Methotrexate, (MTX) and polyherbal extracts for enhanced cancer therapy. Nanoparticles were synthesized using soya lecithin and evaluated for particle size (310 nm), zeta potential (-18.3 mV), encapsulation efficiency (79.71%), FTIR compatibility, and stability. Stability studies demonstrated the formulation's robustness at room temperature for three months. The results underscore the promise of phytosomal nanoparticles in optimizing herbal-based therapeutic strategies, highlighting their potential for enhanced cancer therapy.

International Journal of Pharmacognosy and Life ScienceVol. 6(1)
Zero hunger
Openalex Percentile: Top 95%
Toxin Mechanisms and Immunotoxins
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