Integrating green analytical chemistry and analytical quality by design: an innovative approach for RP-UPLC method development of ensifentrine in bulk and inhalation formulations
This study presents a sensitive and robust RP-UPLC method for quantifying Ensifentrine, combining AQbD and GAC principles. The method, validated according to ICH guidelines, also ensures environmental sustainability. This approach sets a precedent for future analytical method development in pharmaceutical sciences with a focus on sustainability.
Authors
- Praveen Kumar Kusuma (ORCID: https://orcid.org/0000-0002-0854-3734)
- Chandrashekar Thalluri (ORCID: https://orcid.org/0000-0001-8859-8315)
- Bayapa Reddy Narapureddy (ORCID: https://orcid.org/0000-0002-7084-2014)
- Sarad Pawar Naik Bukke (ORCID: https://orcid.org/0000-0002-5693-2953)
- Mohan Goud Vanga
Institutions
- Kampala International University (UG)
- Delhi Pharmaceutical Science and Research University (IN)
- Assam Down Town University (IN)
- King Khalid University (SA)
Publication Details
- Journal
- BMC Chemistry
- Published
- 2025-03-15
- DOI
- https://doi.org/10.1186/s13065-025-01448-8
- Citations
- 7
- Primary Topic
- Chemistry and Chemical Engineering
- Type
- article
- Field-Weighted Citation Impact
- 6.02