Schisandrin B exerts anti-colorectal cancer effect through CXCL2/ERK/DUSP11 signaling pathway
Sch B showed obviously anti-cancer effect to the CRC through inhibiting CXCL2/ERK/DUSP11 axis, but more experiments are needed to figure out the target of Sch B and validate this mechanism in vivo.
Authors
- Liya Ye (ORCID: https://orcid.org/0009-0001-4956-817X)
- Mao Tang
- Wansheng Chen (ORCID: https://orcid.org/0000-0002-0025-1315)
- Zhengyan Liang
- Shouhong Gao (ORCID: https://orcid.org/0000-0002-8322-4637)
- Yunlei Yun
- Zhipeng Wang (ORCID: https://orcid.org/0000-0003-4415-7213)
- Zhijun Liu (ORCID: https://orcid.org/0000-0001-5533-3038)
- Lili Cui (ORCID: https://orcid.org/0000-0002-1496-1879)
- Yingqi Feng (ORCID: https://orcid.org/0000-0003-2854-3974)
- Jianguo Sun
Institutions
- Yunnan University of Traditional Chinese Medicine (CN)
- Zhongkai University of Agriculture and Engineering (CN)
Publication Details
- Journal
- Cancer Cell International
- Published
- 2025-03-15
- DOI
- https://doi.org/10.1186/s12935-025-03727-9
- Citations
- 2
- Primary Topic
- Plant-derived Lignans Synthesis and Bioactivity
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- Bethune Charitable Foundation
- Shanghai Municipal Health Commission
- National Natural Science Foundation of China