Serotonergic Antidepressant Use and Risk of Clinically Significant Bleeding in Thrombocytopenic Hematologic Malignancy Patients

In patients with HM and thrombocytopenia, SRI exposure was not associated with an increased risk of CSB. Given the small study size, assessment of patient-specific risks versus benefits should still be considered when prescribing SRI therapy in this patient population.

Authors

Marissa Olson (ORCID: https://orcid.org/0000-0003-1537-7145)
Emily Owen (ORCID: https://orcid.org/0000-0002-6095-4805)
Colleen McEvoy (ORCID: https://orcid.org/0009-0008-2566-191X)
Eunsun Gill (ORCID: https://orcid.org/0000-0002-3504-2070)
Hannah Delp

Institutions

Barnes-Jewish Hospital (US)
Washington University in St. Louis (US)

Publication Details

Journal: Annals of Pharmacotherapy
Published: 2025-03-15
DOI: https://doi.org/10.1177/10600280251319757
Primary Topic: Cancer Treatment and Pharmacology
Type: article
Field-Weighted Citation Impact: 0.00

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article

Serotonergic Antidepressant Use and Risk of Clinically Significant Bleeding in Thrombocytopenic Hematologic Malignancy Patients

Marissa Olson, Emily Owen, Colleen McEvoy, Eunsun Gill et al.

Mar 15, 2025

Annals of Pharmacotherapy

Cancer Treatment and Pharmacology

article

Serotonergic Antidepressant Use and Risk of Clinically Significant Bleeding in Thrombocytopenic Hematologic Malignancy Patients

Marissa Olson, Emily Owen, Colleen McEvoy, Eunsun Gill, Hannah Delp

March 15, 2025article en

Abstract

In patients with HM and thrombocytopenia, SRI exposure was not associated with an increased risk of CSB. Given the small study size, assessment of patient-specific risks versus benefits should still be considered when prescribing SRI therapy in this patient population.

Annals of PharmacotherapyVol. 59(11)

Barnes-Jewish Hospital (US), Washington University in St. Louis (US)

Good health and well-being

Openalex Percentile: Top 93%

Cancer Treatment and Pharmacology

DOI Source OpenAlex

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