Treatment of an Osteochondral Defect of the Trochlea Using Matrix‐Induced Autologous Chondrocyte Implantation and Proximal Tibia Autologous Bone Grafting

Chondral and osteochondral defects of the knee are painful and disabling in the short term, can lead to accelerated osteoarthritis in the long term, and have relatively poor healing potential. Although many cartilage restoration procedures exist for focal cartilage defects, matrix-induced autologous chondrocyte implantation (MACI) for the appropriate patient has evolved as a reliable technique with encouraging long-term outcomes. Despite the reported favorable outcomes, there remains a relative dearth of literature on the use of MACI with autologous bone graft. This article presents a modified MACI sandwich technique that uses only 1 scaffold in combination with autologous bone graft from the proximal tibia to address an osteochondritis dissecans lesion of the lateral trochlea. This technique allows for both a stable MACI single-layer scaffold and a relatively efficient operative workflow.

Authors

Institutions

Publication Details

Journal
Arthroscopy Techniques
Published
2025-03-15
DOI
https://doi.org/10.1016/j.eats.2025.103507
Primary Topic
Osteoarthritis Treatment and Mechanisms
Type
article
Field-Weighted Citation Impact
0.00

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Treatment of an Osteochondral Defect of the Trochlea Using Matrix‐Induced Autologous Chondrocyte Implantation and Proximal Tibia Autologous Bone Grafting

Paul Walker, Thomas J. Kremen, Rishi Trikha, Kristofer J. Jones
Arthroscopy Techniques
Osteoarthritis Treatment and Mechanisms
article

Treatment of an Osteochondral Defect of the Trochlea Using Matrix‐Induced Autologous Chondrocyte Implantation and Proximal Tibia Autologous Bone Grafting

Paul Walker, Thomas J. Kremen, Rishi Trikha, Kristofer J. Jones
article en

Abstract

Chondral and osteochondral defects of the knee are painful and disabling in the short term, can lead to accelerated osteoarthritis in the long term, and have relatively poor healing potential. Although many cartilage restoration procedures exist for focal cartilage defects, matrix-induced autologous chondrocyte implantation (MACI) for the appropriate patient has evolved as a reliable technique with encouraging long-term outcomes. Despite the reported favorable outcomes, there remains a relative dearth of literature on the use of MACI with autologous bone graft. This article presents a modified MACI sandwich technique that uses only 1 scaffold in combination with autologous bone graft from the proximal tibia to address an osteochondritis dissecans lesion of the lateral trochlea. This technique allows for both a stable MACI single-layer scaffold and a relatively efficient operative workflow.

Arthroscopy TechniquesVol. 14(6)
University of California, Los Angeles (US), Orthopaedic Hospital (US)
Arthrex
Openalex Percentile: Top 93%
Osteoarthritis Treatment and Mechanisms
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.