Challenges in predicting PROTAC-mediated protein–protein interfaces with AlphaFold reveal a general limitation on small interfaces

Authors

Paulo C. T. Souza (ORCID: https://orcid.org/0000-0003-0660-1301)
Juliette Martin (ORCID: https://orcid.org/0000-0002-4787-0885)
Gilberto P. Pereira (ORCID: https://orcid.org/0000-0002-6277-0006)
Corentin Gouzien (ORCID: https://orcid.org/0009-0006-1318-2191)

Institutions

Université Claude Bernard Lyon 1 (FR)
École Normale Supérieure de Lyon (FR)
Centre National de la Recherche Scientifique (FR)
Inserm (FR)
Observatoire Océanologique de Banyuls-sur-Mer (FR)
Laboratoire d'Océanographie Microbienne (FR)

Publication Details

Journal: Bioinformatics Advances
Published: 2024-12-26
DOI: https://doi.org/10.1093/bioadv/vbaf056
Citations: 13
Primary Topic: Protein Degradation and Inhibitors
Type: article
Field-Weighted Citation Impact: 3.04

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article

Challenges in predicting PROTAC-mediated protein–protein interfaces with AlphaFold reveal a general limitation on small interfaces

Paulo C. T. Souza, Juliette Martin, Gilberto P. Pereira, Corentin Gouzien

Dec 26, 2024

13 citations

Bioinformatics Advances

Protein Degradation and Inhibitors

3.04

article

Challenges in predicting PROTAC-mediated protein–protein interfaces with AlphaFold reveal a general limitation on small interfaces

Paulo C. T. Souza, Juliette Martin, Gilberto P. Pereira, Corentin Gouzien

December 26, 2024article en

13 citations

Abstract

No abstract available for this paper.

Bioinformatics AdvancesVol. 5(1)

Université Claude Bernard Lyon 1 (FR), École Normale Supérieure de Lyon (FR), Centre National de la Recherche Scientifique (FR), Inserm (FR), Observatoire Océanologique de Banyuls-sur-Mer (FR), Laboratoire d'Océanographie Microbienne (FR)

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Openalex Percentile: Top 8%

Protein Degradation and Inhibitors

3.04

DOI Open Access PDF OpenAlex

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