First report of blaVEB-3 and blaKPC-2 coexistence with a novel blaKPC-2 transposon in Klebsiella michiganensis
To our knowledge, this is the first report of concurrent bla<sub>VEB-3</sub> and bla<sub>KPC-2</sub> in K. michiganensis, along with a novel bla<sub>KPC-2</sub> transposon structure. These findings highlight the urgent need for enhanced surveillance of MDR K. michiganensis to prevent treatment failures.
Authors
- Peibo Yuan (ORCID: https://orcid.org/0000-0001-5061-0331)
- Yu-Xia Zhong (ORCID: https://orcid.org/0000-0002-3128-2712)
- Dingqiang Chen (ORCID: https://orcid.org/0000-0001-8717-1651)
- Zhenbo Xu (ORCID: https://orcid.org/0000-0003-2865-2441)
- Ling Yang (ORCID: https://orcid.org/0009-0006-3974-6100)
- Li Dai (ORCID: https://orcid.org/0000-0002-1178-2488)
Institutions
- First Affiliated Hospital of Guangzhou Medical University (CN)
- Zhujiang Hospital (CN)
- Southern Medical University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Infection Genetics and Evolution
- Published
- 2025-03-15
- DOI
- https://doi.org/10.1016/j.meegid.2025.105740
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- China Primary Health Care Foundation
- Special Fund Project for Science and Technology Innovation Strategy of Guangdong Province