Tuberculosis epididymitis presenting as an acute scrotum in a 65 year-old man undergoing BCG treatment for bladder cancer

Intravesical immunotherapy with Bacillus Calmette-Guérin (BCG) is the cornerstone of treatment for non-muscle invasive bladder cancer (NMIBC). Intravesical BCG therapy is not without risks however, with complications ranging from bothersome to life-threatening occurring in approximately 1 % of cases. Tuberculous epididymitis is a rare but notable complication of BCG therapy, characterised by granulomatous inflammation of the epididymis. Here we present a rare case of tuberculosis epididymitis in a 65-year-old gentleman receiving intravesical BCG for treatment of his NMIBC. The authors wish to highlight the diagnostic consideration of tuberculosis epididymitis in patients presenting with scrotal pain while undergoing BCG treatment.

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Publication Details

Journal
Urology Case Reports
Published
2025-03-15
DOI
https://doi.org/10.1016/j.eucr.2025.103009
Primary Topic
Diagnosis and treatment of tuberculosis
Type
article
Field-Weighted Citation Impact
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article

Tuberculosis epididymitis presenting as an acute scrotum in a 65 year-old man undergoing BCG treatment for bladder cancer

Melvyn Kuan, Matthew Barns, E Powell
Urology Case Reports
Diagnosis and treatment of tuberculosis
article

Tuberculosis epididymitis presenting as an acute scrotum in a 65 year-old man undergoing BCG treatment for bladder cancer

Melvyn Kuan, Matthew Barns, E Powell
article en

Abstract

Intravesical immunotherapy with Bacillus Calmette-Guérin (BCG) is the cornerstone of treatment for non-muscle invasive bladder cancer (NMIBC). Intravesical BCG therapy is not without risks however, with complications ranging from bothersome to life-threatening occurring in approximately 1 % of cases. Tuberculous epididymitis is a rare but notable complication of BCG therapy, characterised by granulomatous inflammation of the epididymis. Here we present a rare case of tuberculosis epididymitis in a 65-year-old gentleman receiving intravesical BCG for treatment of his NMIBC. The authors wish to highlight the diagnostic consideration of tuberculosis epididymitis in patients presenting with scrotal pain while undergoing BCG treatment.

Urology Case ReportsVol. 61
Sir Charles Gairdner Hospital (AU)
Good health and well-being
Openalex Percentile: Top 92%
Diagnosis and treatment of tuberculosis
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