Deficit of neuronal EAAT2 impairs hippocampus CA3 neuron’s activity and may induce depressive like behaviors
Our findings revealed that EAAT2 deficit in the CA3 induces depression-like behavior, which offers novel insight into MDD pathophysiology.
Authors
- Qinji Zhou (ORCID: https://orcid.org/0000-0002-0625-5042)
- Xiangyu Chen
- Chong Chen (ORCID: https://orcid.org/0000-0002-0161-6574)
- Peng Xie (ORCID: https://orcid.org/0000-0002-0081-6048)
- Ke Cheng (ORCID: https://orcid.org/0000-0002-6876-5398)
Institutions
- The Affiliated Yongchuan Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2025-03-15
- DOI
- https://doi.org/10.1016/j.jare.2025.03.016
- Citations
- 1
- Primary Topic
- Neuroscience and Neuropharmacology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.91