Characterization of lipid nanoparticles using macro mass photometry: Insights into size and mass
This study represents the first use of mass photometry for LNP analysis, simultaneously characterizing the mass and size of LNPs. It highlights the potential of MMP as a valuable orthogonal tool for LNP characterization and supports LNP formulation development.
Authors
- Andrew D. Baik (ORCID: https://orcid.org/0000-0001-6323-4144)
- Brenda Watt
- Julia A. Townsend (ORCID: https://orcid.org/0000-0002-2132-1052)
- Katherine D. Cygnar (ORCID: https://orcid.org/0000-0002-2056-1353)
- Zhijie Wu (ORCID: https://orcid.org/0000-0002-9981-8114)
- Ivor Crooks
- Yu Shrike Zhang (ORCID: https://orcid.org/0000-0002-0045-0808)
- Jikang Wu (ORCID: https://orcid.org/0000-0003-2888-5659)
- Ning Li (ORCID: https://orcid.org/0000-0001-6750-4308)
Institutions
- Regeneron (United States) (US)
- Teradyne (United States) (US)
- Science Oxford (GB)
Publication Details
- Journal
- Analytica Chimica Acta
- Published
- 2025-03-15
- DOI
- https://doi.org/10.1016/j.aca.2025.343944
- Citations
- 3
- Primary Topic
- Lipid Membrane Structure and Behavior
- Type
- article
- Field-Weighted Citation Impact
- 2.42