Lower body mass index is associated with the achievement of target LDL in patients using PCSK9 inhibitors in Taiwan
Lower BMI at baseline was associated with a higher likelihood of achieving LDL-C < 70 mg/dl after 12 weeks of PCSK9 inhibitor therapy. These findings support personalized strategies for optimizing cholesterol management in statin-intolerant patients while further investigations are required.
Authors
- Sheng-Hsiang Lin
- Wei‐Ting Chang (ORCID: https://orcid.org/0000-0001-9525-2144)
- Feng Yu Kuo (ORCID: https://orcid.org/0000-0002-9254-7753)
- Ching‐Lin Hsieh (ORCID: https://orcid.org/0000-0001-9468-9969)
- Kuan-Chieh Tu
- Min‐Ji Charng (ORCID: https://orcid.org/0000-0002-0949-9026)
- Hung‐I Yeh (ORCID: https://orcid.org/0000-0003-3206-0908)
- Tsung‐Hsien Lin (ORCID: https://orcid.org/0000-0002-7226-8730)
- Yen‐Wen Wu (ORCID: https://orcid.org/0000-0003-1520-1166)
- Chao‐Feng Lin (ORCID: https://orcid.org/0000-0002-6865-855X)
- Ching-Pei Chen (ORCID: https://orcid.org/0000-0003-2823-2025)
- Hui-Wen Lin (ORCID: https://orcid.org/0000-0002-8259-4804)
- Yi‐Heng Li (ORCID: https://orcid.org/0000-0003-0390-2360)
- Po‐Hsun Huang (ORCID: https://orcid.org/0000-0003-1584-6749)
- Po‐Lin Lin (ORCID: https://orcid.org/0000-0002-5664-4193)
- Wei-Wen Lin
Institutions
- National Sun Yat-sen University (TW)
- National Yang Ming Chiao Tung University (TW)
- Kaohsiung Medical University (TW)
- Tunghai University (TW)
- Chang Gung University (TW)
- Kaohsiung Medical University Chung-Ho Memorial Hospital (TW)
- Mackay Memorial Hospital (TW)
- Taipei Veterans General Hospital (TW)
- Chang Gung Memorial Hospital (TW)
- Mackay Medical University (TW)
- Taichung Veterans General Hospital (TW)
- Far Eastern Memorial Hospital (TW)
- Chi Mei Medical Center (TW)
- Kaohsiung Veterans General Hospital (TW)
- National Cheng Kung University Hospital (TW)
- Changhua Christian Hospital (TW)
- National Cheng Kung University (TW)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-03-15
- DOI
- https://doi.org/10.1186/s40001-025-02431-8
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00