Lower body mass index is associated with the achievement of target LDL in patients using PCSK9 inhibitors in Taiwan

Lower BMI at baseline was associated with a higher likelihood of achieving LDL-C < 70 mg/dl after 12 weeks of PCSK9 inhibitor therapy. These findings support personalized strategies for optimizing cholesterol management in statin-intolerant patients while further investigations are required.

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Publication Details

Journal
European journal of medical research
Published
2025-03-15
DOI
https://doi.org/10.1186/s40001-025-02431-8
Primary Topic
Lipoproteins and Cardiovascular Health
Type
article
Field-Weighted Citation Impact
0.00
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article

Lower body mass index is associated with the achievement of target LDL in patients using PCSK9 inhibitors in Taiwan

Sheng-Hsiang Lin, Wei‐Ting Chang, Feng Yu Kuo, Ching‐Lin Hsieh et al.
European journal of medical research
Lipoproteins and Cardiovascular Health
article

Lower body mass index is associated with the achievement of target LDL in patients using PCSK9 inhibitors in Taiwan

Sheng-Hsiang Lin, Wei‐Ting Chang, Feng Yu Kuo, Ching‐Lin Hsieh, Kuan-Chieh Tu, Min‐Ji Charng, Hung‐I Yeh, Tsung‐Hsien Lin, Yen‐Wen Wu, Chao‐Feng Lin, Ching-Pei Chen, Hui-Wen Lin, Yi‐Heng Li, Po‐Hsun Huang, Po‐Lin Lin, Wei-Wen Lin
article en

Abstract

Lower BMI at baseline was associated with a higher likelihood of achieving LDL-C < 70 mg/dl after 12 weeks of PCSK9 inhibitor therapy. These findings support personalized strategies for optimizing cholesterol management in statin-intolerant patients while further investigations are required.

European journal of medical researchVol. 30(1)
National Sun Yat-sen University (TW), National Yang Ming Chiao Tung University (TW), Kaohsiung Medical University (TW), Tunghai University (TW), Chang Gung University (TW), Kaohsiung Medical University Chung-Ho Memorial Hospital (TW), Mackay Memorial Hospital (TW), Taipei Veterans General Hospital (TW), Chang Gung Memorial Hospital (TW), Mackay Medical University (TW), Taichung Veterans General Hospital (TW), Far Eastern Memorial Hospital (TW), Chi Mei Medical Center (TW), Kaohsiung Veterans General Hospital (TW), National Cheng Kung University Hospital (TW), Changhua Christian Hospital (TW), National Cheng Kung University (TW)
Good health and well-being
Openalex Percentile: Top 92%
Lipoproteins and Cardiovascular Health
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