miR-374-5p inhibits osteogenesis by targeting PTEN/PI3K/AKT signaling pathway
Our findings indicate that miR-374-5p inhibits osteogenesis in rat osteoblasts by targeting PTEN and modulating the PI3K/AKT signaling pathway.
Authors
- Gen Long (ORCID: https://orcid.org/0000-0002-4144-1879)
- Hongmeng Cheng
- Yunfei Luo (ORCID: https://orcid.org/0000-0002-6838-5950)
- Zhihua Li (ORCID: https://orcid.org/0000-0003-4820-4603)
- Jun Guo (ORCID: https://orcid.org/0000-0001-9867-2689)
- Pei Wang (ORCID: https://orcid.org/0000-0003-2373-7315)
- Fen Liu (ORCID: https://orcid.org/0000-0001-9446-5340)
- Fei Tong (ORCID: https://orcid.org/0000-0002-9197-8260)
Institutions
- Nanchang University (CN)
- Jiangxi Provincial People's Hospital (CN)
Publication Details
- Journal
- Journal of Orthopaedic Surgery and Research
- Published
- 2025-03-14
- DOI
- https://doi.org/10.1186/s13018-025-05670-x
- Citations
- 3
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 2.81
Funders
- National Natural Science Foundation of China