Synergistic influences of BMP9 and NGF on the osteogenic differentiation of C3H10T1/2 mesenchymal stem cells
The findings unveiled the remarkable synergistic link of BMP9 with NGF in potentiating osteogenic differentiation in C3H10T1/2 MSCs. This dual-factor approach presents a compelling paradigm for advancing bone regeneration strategies, providing substantial promise for utilization in bone tissue engineering plus regenerative medicine.
Authors
- Kun Yang (ORCID: https://orcid.org/0000-0002-7720-8681)
- Junyu Liu (ORCID: https://orcid.org/0000-0002-4293-1247)
- Yinghui Tan (ORCID: https://orcid.org/0000-0003-1060-7845)
Institutions
- Army Medical University (CN)
- Zunyi Medical University (CN)
- Xinqiao Hospital (CN)
- Stomatological Hospital of Chongqing Medical University (CN)
- Stomatology Hospital (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Journal of Orthopaedic Surgery and Research
- Published
- 2025-03-15
- DOI
- https://doi.org/10.1186/s13018-025-05669-4
- Citations
- 1
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 1.63
Funders
- National Natural Science Foundation of China