Relationship between sputum bacterial load and lung function in children with cystic fibrosis receiving tobramycin
A greater reduction in total sputum P. aeruginosa bacterial load (live + dead) was associated with improved lung function (FEV<sub>1</sub>) in children with CF receiving tobramycin.
Authors
- Indy Sandaradura (ORCID: https://orcid.org/0000-0002-9457-8262)
- Sarah Sims (ORCID: https://orcid.org/0000-0002-9505-5498)
- Tony Lai (ORCID: https://orcid.org/0000-0001-9761-0072)
- Stephen B. Duffull (ORCID: https://orcid.org/0000-0002-6545-9408)
- Amanda Gwee (ORCID: https://orcid.org/0000-0003-4016-8986)
- Philip Robinson (ORCID: https://orcid.org/0000-0001-6129-9075)
- Shivanthan Shanthikumar (ORCID: https://orcid.org/0000-0001-6000-3180)
- Catherine Satzke (ORCID: https://orcid.org/0000-0003-3164-8849)
- Casey L. Pell (ORCID: https://orcid.org/0000-0003-3883-2163)
- S Ranganathan
- L F Garc a
- Rogers Gb
- Taylor Sl
Institutions
- Royal Children's Hospital (AU)
- Children's Hospital at Westmead (AU)
- Peter Doherty Institute (AU)
- Certara (United States) (US)
- South Australian Health and Medical Research Institute (AU)
- Murdoch Children's Research Institute (AU)
Publication Details
- Journal
- Respiratory Medicine
- Published
- 2025-03-14
- DOI
- https://doi.org/10.1016/j.rmed.2025.108042
- Primary Topic
- Cystic Fibrosis Research Advances
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Melbourne
- Medical Research Council
- National Health and Medical Research Council