Synthesis and Antibacterial Studies of Metal N-Heterocyclic Carbene

To create both symmetrically and unsymmetrically substituted salts, various benzyl and phenyl acetamides were substituted to create benzimidazolium salts. Both symmetrically and unsymmetrically substituted benzimidazolium salts were reacted with Ag2O using the in-situ deprotonation technique to produce silver(I) complex, which produced high-quality derived structures. Ag(I)-NHC complex make N-heterocyclic carbene complexes like Pd(II)-NHC by performing as transfer reagents throughout the transmetallation process. The antibacterial properties of benzimidazolium salts and their corresponding Ag(I) and Pd(II)-NHC complexes are demonstrated. When comparing the Ag(I) silver complex with the benzamidazole salt and the Pd(II) complex, the silver complex showed clear activity.

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Publication Details

Journal
Cognizance Journal of Multidisciplinary Studies
Published
2025-03-15
DOI
https://doi.org/10.47760/cognizance.2025.v05i03.004
Primary Topic
N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
Type
article
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article

Synthesis and Antibacterial Studies of Metal N-Heterocyclic Carbene

Muhand Dohan Abid
Cognizance Journal of Multidisciplinary Studies
N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
article

Synthesis and Antibacterial Studies of Metal N-Heterocyclic Carbene

Muhand Dohan Abid
article en

Abstract

To create both symmetrically and unsymmetrically substituted salts, various benzyl and phenyl acetamides were substituted to create benzimidazolium salts. Both symmetrically and unsymmetrically substituted benzimidazolium salts were reacted with Ag2O using the in-situ deprotonation technique to produce silver(I) complex, which produced high-quality derived structures. Ag(I)-NHC complex make N-heterocyclic carbene complexes like Pd(II)-NHC by performing as transfer reagents throughout the transmetallation process. The antibacterial properties of benzimidazolium salts and their corresponding Ag(I) and Pd(II)-NHC complexes are demonstrated. When comparing the Ag(I) silver complex with the benzamidazole salt and the Pd(II) complex, the silver complex showed clear activity.

Cognizance Journal of Multidisciplinary StudiesVol. 5(3)
Openalex Percentile: Top 96%
N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
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