European Consensus on Malabsorption—UEG & SIGE, LGA, SPG, SRGH, CGS, ESPCG, EAGEN, ESPEN, and ESPGHAN

Malabsorption is a complex and multifaceted condition characterised by the defective passage of nutrients into the blood and lymphatic streams. Several congenital or acquired disorders may cause either selective or global malabsorption in both children and adults, such as cystic fibrosis, exocrine pancreatic insufficiency (EPI), coeliac disease (CD) and other enteropathies, lactase deficiency, small intestinal bacterial overgrowth (SIBO), autoimmune atrophic gastritis, Crohn's disease, and gastric or small bowel resections. Early recognition of malabsorption is key for tailoring a proper diagnostic work-up for identifying the cause of malabsorption. Patient's medical and pharmacological history are essential for identifying risk factors. Several examinations like endoscopy with small intestinal biopsies, non-invasive functional tests, and radiologic imaging are useful in diagnosing malabsorption. Due to its high prevalence, CD should always be looked for in case of malabsorption with no other obvious explanations and in high-risk individuals. Nutritional support is key in management of patients with malabsorption; different options are available, including oral supplements, enteral or parenteral nutrition. In patients with short bowel syndrome, teduglutide proved effective in reducing the need for parenteral nutrition, thus improving the quality of life of these patients. Primary care physicians have a central role in early detection of malabsorption and should be involved into multidisciplinary teams for improving the overall management of these patients. In this European consensus, involving 10 scientific societies and several experts, we have dissected all the issues around malabsorption, including the definitions and diagnostic testing (Part 1), high-risk categories and special populations, nutritional assessment and management, and primary care perspective (Part 2).

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Publication Details

Journal
United European Gastroenterology Journal
Published
2025-03-15
DOI
https://doi.org/10.1002/ueg2.70011
Citations
9
Primary Topic
Digestive system and related health
Type
article
Field-Weighted Citation Impact
16.36

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article

European Consensus on Malabsorption—UEG & SIGE, LGA, SPG, SRGH, CGS, ESPCG, EAGEN, ESPEN, and ESPGHAN

Marco Vincenzo Lenti, S. Schneider, Christos Lionis, Teodora Surdea‐Blaga et al.
9 citations
United European Gastroenterology Journal
Digestive system and related health
16.36
article

European Consensus on Malabsorption—UEG & SIGE, LGA, SPG, SRGH, CGS, ESPCG, EAGEN, ESPEN, and ESPGHAN

Marco Vincenzo Lenti, S. Schneider, Christos Lionis, Teodora Surdea‐Blaga, Marc Sonyi, Juan Manuel Mendive, Aleksejs Derovs, Adriana Nicolau, Johann Hammer, Gonçalo Nunes, Denisa Erhartová, R. Burgos, Jutta Keller, Ilja Tachecí, Juris Pokrotnieks, Jorge Fonseca, Marianna Arvanitakis, Lucrezia Laterza, Jernej Dolinšek, Željko Krznarić, Cristina Maria Sabo, Heinz F. Hammer, Ilse Broekaert, Gino Roberto Corazza, Antonio Di Sabatino, Óscar Segarra, Loris Pironi, Antonio Gasbarrini, Dan Lucian Dumitrascu, Anastasiou Foteini
article en
9 citations

Abstract

Malabsorption is a complex and multifaceted condition characterised by the defective passage of nutrients into the blood and lymphatic streams. Several congenital or acquired disorders may cause either selective or global malabsorption in both children and adults, such as cystic fibrosis, exocrine pancreatic insufficiency (EPI), coeliac disease (CD) and other enteropathies, lactase deficiency, small intestinal bacterial overgrowth (SIBO), autoimmune atrophic gastritis, Crohn's disease, and gastric or small bowel resections. Early recognition of malabsorption is key for tailoring a proper diagnostic work-up for identifying the cause of malabsorption. Patient's medical and pharmacological history are essential for identifying risk factors. Several examinations like endoscopy with small intestinal biopsies, non-invasive functional tests, and radiologic imaging are useful in diagnosing malabsorption. Due to its high prevalence, CD should always be looked for in case of malabsorption with no other obvious explanations and in high-risk individuals. Nutritional support is key in management of patients with malabsorption; different options are available, including oral supplements, enteral or parenteral nutrition. In patients with short bowel syndrome, teduglutide proved effective in reducing the need for parenteral nutrition, thus improving the quality of life of these patients. Primary care physicians have a central role in early detection of malabsorption and should be involved into multidisciplinary teams for improving the overall management of these patients. In this European consensus, involving 10 scientific societies and several experts, we have dissected all the issues around malabsorption, including the definitions and diagnostic testing (Part 1), high-risk categories and special populations, nutritional assessment and management, and primary care perspective (Part 2).

United European Gastroenterology JournalVol. 13(5)
Università Cattolica del Sacro Cuore (IT), Universitat Autònoma de Barcelona (ES), Université Libre de Bruxelles (BE), University Hospital Centre Zagreb (HR), University of Crete (GR), Universität Hamburg (DE), University of Cologne (DE), University of Zagreb (HR), Université Côte d'Azur (FR), Medical University of Graz (AT), Iuliu Hațieganu University of Medicine and Pharmacy (RO), Charles University (CZ), University of Pavia (IT), Clinical Emergency Hospital Bucharest (RO), Erasmus Hospital (BE), Agostino Gemelli University Polyclinic (IT), Centre Hospitalier Universitaire de Nice (FR), Escola Superior de Saúde Egas Moniz (PT), University of Maribor (SI), Pauls Stradiņš Clinical University Hospital (LV), Vall d'Hebron Institut de Recerca (ES), Krankenhaus der Augustinerinnen (DE), Azienda USL di Bologna (IT), Riga Stradiņš University (LV), Vall d'Hebron Hospital Universitari (ES), Institute of Clinical and Experimental Medicine (CZ), University Clinical Centre Maribor (SI), University Hospital Hradec Králové (CZ), Israelitisches Krankenhaus (DE), Hospital Garcia de Orta (PT), Policlinico San Matteo Fondazione (IT), Istituti di Ricovero e Cura a Carattere Scientifico (IT), University Hospital Cologne (DE), Universitat de Barcelona (ES), Medical University of Vienna (AT), University of Bologna (IT)
United European Gastroenterology
Zero hunger
Openalex Percentile: Top 1%
Digestive system and related health
16.36
DOIOpen Access PDFOpenAlex
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