Investigating the Mechanism of IFN‐γ‐Inducible Lysosomal Thiol Reductase‐Mediated Inhibition of Breast Cancer Cell Proliferation
This study reveals a potential mechanism by which GILT can slow breast cancer growth, as well as identifying the possible clinical application value of small molecule inhibitor OICR-9429. These data collectively provide novel treatment strategies for breast cancer therapy.
Authors
- Le Chen (ORCID: https://orcid.org/0000-0003-4963-025X)
- Xiaoqing Guan (ORCID: https://orcid.org/0000-0001-8010-5715)
- You-Cheng Shao
- Hui Li (ORCID: https://orcid.org/0000-0001-5207-347X)
- Yihao Tian (ORCID: https://orcid.org/0000-0001-8584-5480)
- Hanhui Liu
- Jingwei Zhang (ORCID: https://orcid.org/0000-0002-4188-2236)
- Xiaoning Yuan
- Lei Wei (ORCID: https://orcid.org/0000-0003-4240-0208)
- Meng-Fei Chu
- Kaixiang Feng (ORCID: https://orcid.org/0000-0001-7831-3072)
- Qin Liu (ORCID: https://orcid.org/0009-0000-1919-8027)
Institutions
- Wuhan University (CN)
- Zhongnan Hospital of Wuhan University (CN)
Publication Details
- Journal
- Cancer Innovation
- Published
- 2025-03-15
- DOI
- https://doi.org/10.1002/cai2.161
- Citations
- 1
- Primary Topic
- Adenosine and Purinergic Signaling
- Type
- article
- Field-Weighted Citation Impact
- 1.12
Funders
- Fundamental Research Funds for the Central Universities