ANTICANCER ACTIVITY OF AMYGDALIN EXTRACTED FROM LOCAL APRICOT KERNELS

The amygdalin was extracted aqueously from the kernels of local apricots at two temperatures (37, 100) C using citric acid.The percentage of amygdalin extracted at 100 C and 37 C was (68.2) and (20.3) ppm, respectively.Amygdalin was used for the purpose of studying its anti-cancer activity using the MCF-7 breast cancer cell line, compared with the liver cell line (WRL-68).Cell viability at a concentration of 25 mg/ml was (82.8) for MCF-7 breast cancer cells compared to the liver cells (WRL-68) was (94.2) at the same concentration.(IC50) for MCF-7 breast cancer cells was 82.74, and 133.9 for liver cells (WRL-68).

Publication Details

Journal
PLANT ARCHIVES
Published
2024-10-11
DOI
https://doi.org/10.51470/plantarchives.2025.v25.supplement-1.377
Primary Topic
Phytochemicals and Antioxidant Activities
Type
article
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article

ANTICANCER ACTIVITY OF AMYGDALIN EXTRACTED FROM LOCAL APRICOT KERNELS

PLANT ARCHIVES
Phytochemicals and Antioxidant Activities
article

ANTICANCER ACTIVITY OF AMYGDALIN EXTRACTED FROM LOCAL APRICOT KERNELS

article en

Abstract

The amygdalin was extracted aqueously from the kernels of local apricots at two temperatures (37, 100) C using citric acid.The percentage of amygdalin extracted at 100 C and 37 C was (68.2) and (20.3) ppm, respectively.Amygdalin was used for the purpose of studying its anti-cancer activity using the MCF-7 breast cancer cell line, compared with the liver cell line (WRL-68).Cell viability at a concentration of 25 mg/ml was (82.8) for MCF-7 breast cancer cells compared to the liver cells (WRL-68) was (94.2) at the same concentration.(IC50) for MCF-7 breast cancer cells was 82.74, and 133.9 for liver cells (WRL-68).

PLANT ARCHIVESVol. 25(1)
Zero hunger
Openalex Percentile: Top 78%
Phytochemicals and Antioxidant Activities
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ANTICANCER ACTIVITY OF AMYGDALIN EXTRACTED FROM LOCAL APRICOT KERNELS · PLANT ARCHIVES (2024) | TGRS Research Map | TGRS