Analysis of <i>In Vitro</i> Mirtazapine Metabolites in Human Liver Microsomes by LC-HRMS.

The metabolites discovered in this study are consistent with the main metabolites of mirtazapine reported in literature, which are N-desmethylmetazapine, 8-hydroxy mirtazapine and mirtazapine-N-oxide. The results can provide basis for the confirmation of mirtazapine cases and provide reference for the study of other substances.

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Publication Details

Journal
PubMed
Published
2024-12-25
DOI
https://doi.org/10.12116/j.issn.1004-5619.2024.340606
Primary Topic
Alkaline Phosphatase Research Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Analysis of In Vitro Mirtazapine Metabolites in Human Liver Microsomes by LC-HRMS.

Duoqi Xu, Shiyang Qin, Ying Zhang, Jing Qiao et al.
PubMed
Alkaline Phosphatase Research Studies
article

Analysis of In Vitro Mirtazapine Metabolites in Human Liver Microsomes by LC-HRMS.

Duoqi Xu, Shiyang Qin, Ying Zhang, Jing Qiao, Wenfang Zhang
article en

Abstract

The metabolites discovered in this study are consistent with the main metabolites of mirtazapine reported in literature, which are N-desmethylmetazapine, 8-hydroxy mirtazapine and mirtazapine-N-oxide. The results can provide basis for the confirmation of mirtazapine cases and provide reference for the study of other substances.

PubMedVol. 40(6)
Ministry of Public Security of the People's Republic of China (CN), Shanghai Public Security Bureau (CN), Institute of Forensic Science (CN)
Openalex Percentile: Top 60%
Alkaline Phosphatase Research Studies
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