Hyperpigmentation of the oral mucosa caused by dietary beta carotene: a case report.

Chronic ingestion of foods containing elevated levels of beta carotene, a common dietary staple endemic in West Africa, may promote the development of yellow to orange hyperpigmentation of the oral mucosa and skin. This benign condition, known as carotenemia or hypercarotenemia, has received little attention in the general dental literature. The aim of this case report is to increase awareness of this phenomenon by describing the clinical presentation of a patient from Nigeria with conspicuous yellow discoloration of the floor of the mouth and soft palatal mucosa. Attending clinicians should seek clinicopathologic correlations of yellow mucocutaneous discoloration, most notably jaundice associated with hepatitis. In this case, the patient's normal liver biomarkers, absence of dermal manifestations, and high intake of beta carotene-rich foods led to a diagnosis of carotenemia.

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Publication Details

Journal
PubMed
Published
2025-03-13
Primary Topic
Acne and Rosacea Treatments and Effects
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article
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article

Hyperpigmentation of the oral mucosa caused by dietary beta carotene: a case report.

Danielle Mazza, Ahmed S. Sultan, John K Brooks, Joo‐Hang Kim
PubMed
Acne and Rosacea Treatments and Effects
article

Hyperpigmentation of the oral mucosa caused by dietary beta carotene: a case report.

Danielle Mazza, Ahmed S. Sultan, John K Brooks, Joo‐Hang Kim
article en

Abstract

Chronic ingestion of foods containing elevated levels of beta carotene, a common dietary staple endemic in West Africa, may promote the development of yellow to orange hyperpigmentation of the oral mucosa and skin. This benign condition, known as carotenemia or hypercarotenemia, has received little attention in the general dental literature. The aim of this case report is to increase awareness of this phenomenon by describing the clinical presentation of a patient from Nigeria with conspicuous yellow discoloration of the floor of the mouth and soft palatal mucosa. Attending clinicians should seek clinicopathologic correlations of yellow mucocutaneous discoloration, most notably jaundice associated with hepatitis. In this case, the patient's normal liver biomarkers, absence of dermal manifestations, and high intake of beta carotene-rich foods led to a diagnosis of carotenemia.

PubMedVol. 73(1)
Openalex Percentile: Top 90%
Acne and Rosacea Treatments and Effects
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