Widespread decoupling of spindles and slow waves in temporal lobe epilepsy
Despite a focal epileptic generator, patients with unilateral TLE showed a widespread decoupling between sleep spindles and SWs that was most prominent in early sleep. As coupling was shown to be associated with neuropsychological performance in healthy people, this global decoupling may constitute one potential mechanism of poor memory performance in people with TLE.
Authors
- Erica Minato
- Alfonso Garcia‐Asensi
- Chifaou Abdallah (ORCID: https://orcid.org/0000-0001-7232-6673)
- Kassem Jaber
- Katharina Schiller (ORCID: https://orcid.org/0000-0002-2163-3857)
- Jean Gotman (ORCID: https://orcid.org/0000-0002-9796-5946)
- Birgit Frauscher (ORCID: https://orcid.org/0000-0001-6064-1529)
- Nicolás von Ellenrieder (ORCID: https://orcid.org/0000-0003-0845-347X)
- John Thomas (ORCID: https://orcid.org/0000-0003-0144-3746)
- Daniel Mansilla (ORCID: https://orcid.org/0000-0002-5445-2526)
Institutions
- Montreal Neurological Institute and Hospital (CA)
- Duke University (US)
- University Hospital Augsburg (DE)
- Sensor-Technik Wiedemann (Germany) (DE)
- Duke University Hospital (US)
- McGill University (CA)
Publication Details
- Journal
- Epilepsia
- Published
- 2025-03-14
- DOI
- https://doi.org/10.1111/epi.18359
- Citations
- 4
- Primary Topic
- Sleep and Wakefulness Research
- Type
- article
- Field-Weighted Citation Impact
- 5.72
Funders
- Deutsche Forschungsgemeinschaft
- Canadian Institutes of Health Research