Hydrogen sulfide attenuates oxidative stress-induced cellular senescence via the Sirt3/SOD2 signaling pathway in chronic obstructive pulmonary disease
Our study indicates that H 2 S inhibits oxidative stress and cellular senescence by modulating the Sirt3/SOD2 signaling pathway, therefore attenuating the emphysema and impaired lung function induced by CS.
Authors
- Lixiang Xue (ORCID: https://orcid.org/0000-0003-1507-7193)
- Yongfen Qi (ORCID: https://orcid.org/0000-0001-6514-0491)
- Yanling Ding
- Huanyu Long (ORCID: https://orcid.org/0000-0001-7424-3492)
- Yahong Chen (ORCID: https://orcid.org/0000-0003-3258-8032)
- Simin Jiang
- Shurun Li
- Jing Fan (ORCID: https://orcid.org/0000-0002-1919-3354)
- Sha Liao
- Dian Chen (ORCID: https://orcid.org/0000-0002-2911-9019)
Institutions
- Peking University (CN)
- Peking University Third Hospital (CN)
Publication Details
- Journal
- Chinese Medical Journal
- Published
- 2025-03-14
- DOI
- https://doi.org/10.1097/cm9.0000000000003452
- Citations
- 3
- Primary Topic
- Sulfur Compounds in Biology
- Type
- article
- Field-Weighted Citation Impact
- 3.34