Hepatocyte‐specific <scp>RAP1B</scp> deficiency ameliorates high‐fat diet‐induced obesity and liver inflammation in mice

This study highlights RAP1B's pivotal role in hepatic metabolism and positions it as a potential therapeutic target for obesity and related metabolic disorders.

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Publication Details

Journal
Diabetes Obesity and Metabolism
Published
2025-03-13
DOI
https://doi.org/10.1111/dom.16309
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Hepatocyte‐specific RAP1B deficiency ameliorates high‐fat diet‐induced obesity and liver inflammation in mice

Yaping Zhou, Yinxu Fu, Yanyang Hu, Qiongya Zhao et al.
Diabetes Obesity and Metabolism
Liver Disease Diagnosis and Treatment
article

Hepatocyte‐specific RAP1B deficiency ameliorates high‐fat diet‐induced obesity and liver inflammation in mice

Yaping Zhou, Yinxu Fu, Yanyang Hu, Qiongya Zhao, Kaiqiang Yang, Liqin Jin, Ping Hu, E. R. Gritskevitch, Jianxin Lyu, Weijia Li, Yu Fang, Yu Shi, Ting Fu
article en

Abstract

This study highlights RAP1B's pivotal role in hepatic metabolism and positions it as a potential therapeutic target for obesity and related metabolic disorders.

Diabetes Obesity and MetabolismVol. 27(6)
Wenzhou Medical University (CN), Belarusian State University (BY), Zhejiang Provincial People's Hospital (CN), Hangzhou Medical College (CN), International Sakharov Environmental Institute (BY)
National Natural Science Foundation of China
Zero hunger
Openalex Percentile: Top 93%
Liver Disease Diagnosis and Treatment
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Hepatocyte‐specific <scp>RAP1B</scp> deficiency ameliorates high‐fat diet‐induced obesity and liver inflammation in mice — Yaping Zhou, Yinxu Fu, et al. · Diabetes Obesity and Metabolism (2025) | TGRS Research Map | TGRS