Leukoencephalopathy following stereotactic radiosurgery for breast cancer brain metastases: a single-center analysis of 1,077 lesions
Our findings demonstrated that WBRT plus SRS is associated with higher leukoencephalopathy rates than SRS alone. This underscores the importance of carefully weighing the benefits and risks of different ionizing radiation approaches in the management of brain metastasis from breast cancer.
Authors
- Jason Sheehan (ORCID: https://orcid.org/0000-0002-0025-9886)
- David Schlesinger
- Mariam Ishaque (ORCID: https://orcid.org/0000-0002-9488-936X)
- Purushotham Ramanathan
- Bardia Hajikarimloo (ORCID: https://orcid.org/0000-0001-8801-1158)
- Salem M Tos (ORCID: https://orcid.org/0000-0001-7154-6869)
- Georgios Mantziaris (ORCID: https://orcid.org/0000-0002-3389-8836)
Institutions
- University of Virginia (US)
Publication Details
- Journal
- Acta Neurochirurgica
- Published
- 2025-03-14
- DOI
- https://doi.org/10.1007/s00701-025-06478-8
- Primary Topic
- Brain Metastases and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00