Neutrophil Extracellular Traps Are Widely Distributed Across Lesional and Perilesional Hidradenitis Suppurativa Skin, and Elevated Serum <scp>NET</scp> Markers Associate With Moderate to Severe <scp>HS</scp> Disease
Elevated NET markers are widely distributed in HS skin and serum. These data indicate that NET-associated markers in serum are candidate biomarkers for HS disease severity. The results confirm the rationale for anti-inflammatory therapy targeting NETs in HS.
Authors
- Judy Stein (ORCID: https://orcid.org/0000-0002-3910-5411)
- Eric Meldrum (ORCID: https://orcid.org/0009-0000-8788-8038)
- S. van Dalen (ORCID: https://orcid.org/0000-0003-2419-8544)
- John R Ingram (ORCID: https://orcid.org/0000-0002-5257-1142)
- Piotr K. Krajewski (ORCID: https://orcid.org/0000-0003-4722-8531)
- Maarten van der Linden (ORCID: https://orcid.org/0000-0001-8597-4151)
- Renato G.S. Chirivi (ORCID: https://orcid.org/0000-0003-4546-1559)
- Helmuth van Es
- Errol Prospero Prens (ORCID: https://orcid.org/0000-0002-8158-660X)
- Jacek Cezary Szepietowski (ORCID: https://orcid.org/0000-0003-0766-6342)
- Kelsey R. van Straalen (ORCID: https://orcid.org/0000-0003-3305-3814)
- Tirza Bruurmijn (ORCID: https://orcid.org/0009-0007-1259-4570)
- Martyn Foster
Institutions
- Wrocław University of Science and Technology (PL)
- Erasmus MC (NL)
- Wroclaw Medical University (PL)
- AGH University of Krakow (PL)
- Cardiff University (GB)
Publication Details
- Journal
- International Journal of Dermatology
- Published
- 2025-03-13
- DOI
- https://doi.org/10.1111/ijd.17706
- Citations
- 6
- Primary Topic
- Hidradenitis Suppurativa and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 12.03