Comparison of the clinical and laboratory characteristics of neuromyelitis optica spectrum disorder with or without cerebrospinal fluid oligoclonal bands: a cohort with 36-month follow-up

For AQP4-IgG-positive NMOSD patients, positivity for CSF OCBs is associated with higher CSF cell counts and a higher likelihood to have concomitant CTD and oAIA. OCBs+ is not uncommon in NMOSD and may predict more frequent relapses, but not a more serious illness.

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Publication Details

Journal
Frontiers in Immunology
Published
2025-03-14
DOI
https://doi.org/10.3389/fimmu.2025.1536853
Primary Topic
Multiple Sclerosis Research Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Comparison of the clinical and laboratory characteristics of neuromyelitis optica spectrum disorder with or without cerebrospinal fluid oligoclonal bands: a cohort with 36-month follow-up

Wanqing Wu, Wenbo Yang, Xiangjun Chen, Bo Deng et al.
1 links
Frontiers in Immunology
Multiple Sclerosis Research Studies
article

Comparison of the clinical and laboratory characteristics of neuromyelitis optica spectrum disorder with or without cerebrospinal fluid oligoclonal bands: a cohort with 36-month follow-up

Wanqing Wu, Wenbo Yang, Xiangjun Chen, Bo Deng, Hai Yu, Xiaoqin Wu, Xiang Zhang, Jie Wei, Jingguo Wang, Xiaoni Liu
article en

Abstract

For AQP4-IgG-positive NMOSD patients, positivity for CSF OCBs is associated with higher CSF cell counts and a higher likelihood to have concomitant CTD and oAIA. OCBs+ is not uncommon in NMOSD and may predict more frequent relapses, but not a more serious illness.

Frontiers in ImmunologyVol. 16
Fudan University (CN), Huashan Hospital (CN)
Openalex Percentile: Top 93%
Multiple Sclerosis Research Studies
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