Clinicopathological analysis of 13 patients with embryonal rhabdomyosarcoma of the female reproductive system in the Chinese population

ERMS is rare, diagnosed by histology and immunohistochemistry, <i>DICER1</i> mutation may assist. Treatment is surgery + chemo ± radiotherapy, efficacy related to multiple factors. When ERMS is diagnosed, it is mostly in the early stage, and the treatment method is mostly surgery plus chemotherapy with or without radiotherapy. However, the treatment effect is related to factors such as staging, Intergroup Rhabdomyosarcoma Study (IRS) clinical grouping, COG-STS risk, patient age, and TP53 mutation. There is no clear guideline for the treatment of adult patients.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-03-14
DOI
https://doi.org/10.3389/fonc.2025.1546607
Citations
2
Primary Topic
Sarcoma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
3.04
Controls
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article

Clinicopathological analysis of 13 patients with embryonal rhabdomyosarcoma of the female reproductive system in the Chinese population

Liang Sun, Juan Zou, Liping Bai, Yali Chen et al.
2 citations
Frontiers in Oncology
Sarcoma Diagnosis and Treatment
3.04
article

Clinicopathological analysis of 13 patients with embryonal rhabdomyosarcoma of the female reproductive system in the Chinese population

Liang Sun, Juan Zou, Liping Bai, Yali Chen, Ling Han
article en
2 citations

Abstract

ERMS is rare, diagnosed by histology and immunohistochemistry, <i>DICER1</i> mutation may assist. Treatment is surgery + chemo ± radiotherapy, efficacy related to multiple factors. When ERMS is diagnosed, it is mostly in the early stage, and the treatment method is mostly surgery plus chemotherapy with or without radiotherapy. However, the treatment effect is related to factors such as staging, Intergroup Rhabdomyosarcoma Study (IRS) clinical grouping, COG-STS risk, patient age, and TP53 mutation. There is no clear guideline for the treatment of adult patients.

Frontiers in OncologyVol. 15
Sichuan University (CN), West China Second University Hospital of Sichuan University (CN)
Good health and well-being
Openalex Percentile: Top 11%
Sarcoma Diagnosis and Treatment
3.04
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