Clinicopathological analysis of 13 patients with embryonal rhabdomyosarcoma of the female reproductive system in the Chinese population
ERMS is rare, diagnosed by histology and immunohistochemistry, <i>DICER1</i> mutation may assist. Treatment is surgery + chemo ± radiotherapy, efficacy related to multiple factors. When ERMS is diagnosed, it is mostly in the early stage, and the treatment method is mostly surgery plus chemotherapy with or without radiotherapy. However, the treatment effect is related to factors such as staging, Intergroup Rhabdomyosarcoma Study (IRS) clinical grouping, COG-STS risk, patient age, and TP53 mutation. There is no clear guideline for the treatment of adult patients.
Authors
- Liang Sun (ORCID: https://orcid.org/0000-0002-5213-6941)
- Juan Zou (ORCID: https://orcid.org/0000-0002-2500-2454)
- Liping Bai (ORCID: https://orcid.org/0000-0001-8122-0395)
- Yali Chen
- Ling Han (ORCID: https://orcid.org/0000-0001-5219-6410)
Institutions
- Sichuan University (CN)
- West China Second University Hospital of Sichuan University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-03-14
- DOI
- https://doi.org/10.3389/fonc.2025.1546607
- Citations
- 2
- Primary Topic
- Sarcoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 3.04