The inverse relationship between the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and testosterone in adult males in the United States: a cross-sectional study based on the NHANES database
Our study is the first to identify a significant association between elevated NHHR and both reduced total testosterone levels and increased risk of TD in a large, representative sample of adult American males. These findings suggest that NHHR could serve as a valuable marker for early identification of individuals at risk for testosterone decline and TD, enabling timely and targeted clinical interventions.
Authors
- Rui Xu (ORCID: https://orcid.org/0000-0002-7157-3805)
- Xingliang Feng (ORCID: https://orcid.org/0000-0002-0003-0301)
- Yiming Chen (ORCID: https://orcid.org/0000-0002-1501-5550)
- Xiaogang Wang (ORCID: https://orcid.org/0000-0001-9798-834X)
- Renfang Xu (ORCID: https://orcid.org/0000-0002-9880-5653)
- Yangyang Mei (ORCID: https://orcid.org/0009-0005-2508-9851)
Institutions
- Soochow University (CN)
- Jiangyin People's Hospital (CN)
- The First People's Hospital of Changzhou (CN)
- Jinhua Central Hospital (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-03-14
- DOI
- https://doi.org/10.3389/fendo.2025.1478124
- Citations
- 7
- Primary Topic
- Hormonal and reproductive studies
- Type
- article
- Field-Weighted Citation Impact
- 9.06