Analysis of consumption of antibacterial drugs in an ophthalmic surgical hospital

Abstract Antimicrobial therapy management involves the use of methods of clinical-economic and pharmacoepidemiological analysis of antibiotic use in order to improve the clinical and economic effectiveness of therapy. The article presents the results of the analysis of antibacterial drug consumption using the ATC/DDD methodology in an ophthalmic surgical hospital. The aim of this study was to analyze the consumption of antibacterial drugs in an ophthalmic surgical hospital. Material and methods. The ATC/DDD methodology recommended by WHO as a standard for drug statistics research was used to analyze the consumption of antibacterial drugs. The use of ophthalmic antibacterial drugs (drugs of the S01A group according to the ATC classification) from 2017 to 2023 was assessed. The density of antibacterial drug use was estimated by the ratio of DDD / 100 operated patients. Results and discussion. During the observation period, the consumption of antibacterial drugs decreased by almost 8 times, financial costs – by 2 times. Changes in the structure of the applied groups of antibacterial agents were established: a decrease in antibiotics of the fluoroquinolone groups of the second generation, chloramphenicol, an increase in aminoglycosides of the second generation, fluoroquinolones of the third and fourth generations. Conclusions. Changes in the general structure of antibiotic consumption lead to an increase in the effectiveness of the applied treatment and prevention regimens and, as a consequence, to a decrease in drug consumption and financial costs for drugs of this group