Causal association between blood metabolites and head and neck cancer: butyrylcarnitine identified as an associated trait for cancer risk and progression
By employing a genetic epidemiological framework, our research assessed the impact of metabolite butyrylcarnitine on HNC susceptibility. These findings offer valuable insights into potential therapeutic targets and highlight the promise of targeted metabolic strategies for reducing HNC risk. Nevertheless, further research is required to elucidate the precise biological mechanisms underlying these findings.
Authors
- Sufang Qiu (ORCID: https://orcid.org/0000-0001-7660-6955)
- Ying Li (ORCID: https://orcid.org/0000-0002-0233-646X)
- Jue Wang (ORCID: https://orcid.org/0000-0002-9948-4783)
- Jing Wang (ORCID: https://orcid.org/0009-0007-9352-2850)
- Zihan Chen (ORCID: https://orcid.org/0009-0006-3412-0897)
- Jinghua Lai (ORCID: https://orcid.org/0009-0005-4528-7564)
- Libin Zhang (ORCID: https://orcid.org/0009-0006-7620-3957)
- Zongwei Huang (ORCID: https://orcid.org/0000-0003-0981-2999)
- Ruyu Lin
- Lizhu Lin (ORCID: https://orcid.org/0009-0001-7891-5521)
Institutions
- Fujian Medical University (CN)
- Fujian Provincial Cancer Hospital (CN)
Publication Details
- Journal
- Hereditas
- Published
- 2025-03-14
- DOI
- https://doi.org/10.1186/s41065-025-00408-5
- Citations
- 1
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.94