Investigating the therapeutic potential of naringin in MK-801-induced schizophrenia model: focus on cognitive impairment and miR-25-3p-regulated pathways
NR may protect neurons in the CA1 region of the hippocampus and enhance synaptic plasticity by regulating the miR-25-3p/SIK1/CRTC2/CREB1 signaling pathway, thereby promoting cognitive improvement.
Authors
- Yiyong Xu
- Hongyan Xiao (ORCID: https://orcid.org/0000-0002-9362-3850)
- Xinyi Xu (ORCID: https://orcid.org/0000-0003-4703-4040)
- Y. N. Pu (ORCID: https://orcid.org/0009-0004-6272-3543)
- Zushun Zhuo
Institutions
- Jiangxi University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- International Journal of Neuroscience
- Published
- 2025-03-14
- DOI
- https://doi.org/10.1080/00207454.2025.2478825
- Primary Topic
- Cytokine Signaling Pathways and Interactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00