Case report: single-cell transcriptome sequencing reveals the clonal origin of mature plasmacytoid dendritic cell proliferation in early T-cell precursor lymphoblastic leukemia
This case highlights the presence of MPDCP in lymphoid malignancies and utilizes single-cell RNA sequencing technology to provide insights into the potential link between pDC and lymphocyte differentiation and development. However, further studies are needed to confirm these findings and explore their clinical implications.
Authors
- Longyi Zhang (ORCID: https://orcid.org/0000-0003-3625-489X)
- Yan Lu (ORCID: https://orcid.org/0009-0005-2939-8029)
- Jinwen Jiang
- Gongqiang Wu
Institutions
- Wenzhou Medical University (CN)
- Dongyang People's Hospital (CN)
Publication Details
- Journal
- Annals of Hematology
- Published
- 2025-03-14
- DOI
- https://doi.org/10.1007/s00277-025-06301-5
- Citations
- 1
- Primary Topic
- CAR-T cell therapy research
- Type
- article
- Field-Weighted Citation Impact
- 1.05