Inonotus obliquus (chaga) ameliorates folic acid-induced renal fibrosis in mice: the crosstalk analysis among PT cells, macrophages and T cells based on single-cell sequencing
Our study provided new insights into the potential therapeutic effects of Chaga in renal fibrosis through single-cell sequencing analysis. Our findings suggest that Chaga may represent a promising candidate for renal fibrosis treatment, though further experimental validation is needed to establish its clinical application.
Authors
- Rongshan Li (ORCID: https://orcid.org/0000-0002-8082-4389)
- Xinyu Wang (ORCID: https://orcid.org/0000-0002-3173-6390)
- Xuemei Liu (ORCID: https://orcid.org/0000-0001-5852-6134)
- Rui Wang (ORCID: https://orcid.org/0009-0003-1516-3865)
- Hui Liao (ORCID: https://orcid.org/0000-0002-1165-2907)
- Yue-Ling Peng
- Yaling Zhang
Institutions
- Shanxi Medical University (CN)
- Taiyuan Central Hospital (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-03-14
- DOI
- https://doi.org/10.3389/fphar.2025.1556739
- Citations
- 1
- Primary Topic
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.80