Faecal Cytolysin is Associated With Worse Survival in Patients With Primary Sclerosing Cholangitis
Our data highlight the association of E. faecalis and faecal cytolysin with lower survival in patients with PSC. These data should prompt further research into the pathogenic role of cytolysin-positive E. faecalis, and to explore its role as a potential therapeutic target.
Authors
- Bernd Schnabl (ORCID: https://orcid.org/0000-0002-6281-825X)
- Hilmar Berger (ORCID: https://orcid.org/0000-0002-6304-4946)
- Fernanda Raya Tonetti (ORCID: https://orcid.org/0000-0002-8890-4252)
- Burcin Özdirik (ORCID: https://orcid.org/0000-0002-8885-737X)
- Nicole Treichel
- Noemí Cabré (ORCID: https://orcid.org/0000-0002-7473-8898)
- Thomas Clavel (ORCID: https://orcid.org/0000-0002-7229-5595)
- Michael Sigal (ORCID: https://orcid.org/0000-0003-4772-0761)
- Frank Tacke (ORCID: https://orcid.org/0000-0001-6206-0226)
Institutions
- University of California San Diego (US)
- VA San Diego Healthcare System (US)
- Charité - Universitätsmedizin Berlin (DE)
- RWTH Aachen University (DE)
Publication Details
- Journal
- Liver International
- Published
- 2025-03-14
- DOI
- https://doi.org/10.1111/liv.16181
- Citations
- 4
- Primary Topic
- Liver Diseases and Immunity
- Type
- article
- Field-Weighted Citation Impact
- 5.29
Funders
- Office of Research and Development
- Deutsche Forschungsgemeinschaft