Treatment of Noncompressible Torso Hemorrhage With Thermoreversible Intra-abdominal Foam: A Dose-response Study in a Porcine Model
Pressure is the gold standard for effective tamponade of bleeding. In this dose-finding study of the F.O.A.M. device for intra-abdominal tamponade of NCTH in a porcine model, we found a 95% posterior probability that either 70 mmHg or 80 mmHg is the minimum effective pressure as defined in our model. Future studies will be needed to assess long-term survival and adverse events at this pressure.
Authors
- Diane Goldenberg (ORCID: https://orcid.org/0000-0001-9701-5070)
- John Cambridge
- Jonathan K. Armstrong
- Oliver J Buchanan
- Juliana Tolles (ORCID: https://orcid.org/0000-0002-4352-2998)
- James D. Ross (ORCID: https://orcid.org/0000-0002-5767-6605)
- Ross I. Donaldson (ORCID: https://orcid.org/0000-0002-5640-582X)
- David A. Tanen (ORCID: https://orcid.org/0000-0002-7756-6649)
- Todd Graham (ORCID: https://orcid.org/0000-0002-2255-6603)
- Aslam A Akhtar
- Maja Engler
Institutions
- UCLA Medical Center (US)
- Critical Innovations (United States) (US)
- Harbor–UCLA Medical Center (US)
Publication Details
- Journal
- Journal of Surgical Research
- Published
- 2025-03-14
- DOI
- https://doi.org/10.1016/j.jss.2025.02.003
- Citations
- 2
- Primary Topic
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Type
- article
- Field-Weighted Citation Impact
- 3.09