Community Pharmacists’ Responses Toward Antimicrobial Prescriptions in Jordan: A Cross-Sectional Survey

<b>Background:</b> Globally, community pharmacists worldwide have prescribed more over-the-counter systemic antibiotics, posing significant issues for international organizations tackling antibiotic-resistant bacteria, a major global threat, due to the accessibility in pharmacies. <b>Objectives:</b> This study aimed to examine the Jordanian pharmacists' antibiotic selection and over-the-counter antibiotic prescriptions. <b>Methods:</b> A total of 244 community pharmacists participated in an online standardized survey, which examined five essential domains including sources and trust of pharmacy antibiotic prescription information, category and frequency of permitted antimicrobials, prescription-free antimicrobials, interactions, antimicrobial prescription issues for pharmacists, and pharmacy staff's knowledge of non-prescription antimicrobial questions and answers. <b>Results:</b> This study found that 1-pharmacists are confident in prescribing antibiotics and they use various tools to improve their skills. 2-Antibiotics were the most sought antimicrobials without a prescription, followed by antifungals and antivirals. 3-Throat, urinary tract, chest, and otitis media are the most common infections that require antibiotics. Pharmacists prescribe penicillin for 75% of throat infections, Fluoroquinolones for 48.2% of urinary tract infections, and cephalosporins for 35.9%. Macrolides are the most prevalent otitis media treatment (43.2%). 4-Some people obtain antimicrobial prescriptions without a valid reason or diagnosis. 5-Many pharmacists (171/244, 70%) agree or strongly believe that antibiotic prescription information is difficult to obtain. 6-Many pharmacists (183/200, 91.5%) aimed to educate patients on the risks and correct use of antimicrobials without prescriptions. <b>Conclusions:</b> These results show that Jordanian community pharmacists follow clinical antibiotic prescribing guidelines and conduct antimicrobial stewardship, yet they demand antimicrobials without prescriptions and lack decision support tools. Antibiotic classes address most diseases, and pharmacists emphasize antimicrobial misuse.