Infant development at 14 months in the context of maternal objective and subjective birth experience and infant hair glucocorticoids

Objective aspects of the birth experience may have a more enduring impact on infant hair GCs than maternal subjective perceptions, particularly with higher birth complications being linked to lower infant cortisone and a higher infant cortisol/cortisone ratio. Given that this ratio may indicate reduced enzymatic activity in converting cortisol to its inactive form, results suggest that birth complications could affect the infant's glucocorticoid metabolism. No robust associations were found between birth experiences or hair GCs and infant development. Further research in more diverse, at-risk populations is needed to clarify these complex relationships.

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Publication Details

Journal
BMC Pediatrics
Published
2025-03-14
DOI
https://doi.org/10.1186/s12887-025-05528-5
Citations
2
Primary Topic
Maternal Mental Health During Pregnancy and Postpartum
Type
article
Field-Weighted Citation Impact
3.76

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article

Infant development at 14 months in the context of maternal objective and subjective birth experience and infant hair glucocorticoids

Susan Garthus‐Niegel, Marlene Karl, Luisa Bergunde, Isabel Jaramillo et al.
2 citations
BMC Pediatrics
Maternal Mental Health During Pregnancy and Postpartum
3.76
article

Infant development at 14 months in the context of maternal objective and subjective birth experience and infant hair glucocorticoids

Susan Garthus‐Niegel, Marlene Karl, Luisa Bergunde, Isabel Jaramillo, Corinna Müller-Stark, Clemens Kirschbaum, Victoria Weise, Susann Steudte‐Schmiedgen
article en
2 citations

Abstract

Objective aspects of the birth experience may have a more enduring impact on infant hair GCs than maternal subjective perceptions, particularly with higher birth complications being linked to lower infant cortisone and a higher infant cortisol/cortisone ratio. Given that this ratio may indicate reduced enzymatic activity in converting cortisol to its inactive form, results suggest that birth complications could affect the infant's glucocorticoid metabolism. No robust associations were found between birth experiences or hair GCs and infant development. Further research in more diverse, at-risk populations is needed to clarify these complex relationships.

BMC PediatricsVol. 25(1)
Norwegian Institute of Public Health (NO), MSH Medical School Hamburg – University of Applied Sciences and Medical University (DE), University Hospital Carl Gustav Carus (DE), Technische Universität Dresden (DE)
Technische Universität Dresden
No poverty
Openalex Percentile: Top 9%
Maternal Mental Health During Pregnancy and Postpartum
3.76
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Infant development at 14 months in the context of maternal objective and subjective birth experience and infant hair glucocorticoids — Susan Garthus‐Niegel, Marlene Karl, et al. · BMC Pediatrics (2025) | TGRS Research Map | TGRS