Modeling the impact of quarantine on COVID-19 transmission: A comprehensive approach

The COVID-19 pandemic has had a profound global impact, necessitating an in-depth understanding of its transmission dynamics. This study presents a dynamic compartmental model that categorizes the population into six compartments: Susceptible (S), Exposed (E), Asymptomatic (A), Symptomatic (I), Quarantine (Q), and Recovered (R). We conduct a thorough analysis of the model, including the computation of the basic reproduction number [Formula: see text] and an examination of equilibrium points and bifurcation behaviors. Our findings indicate that the disease-free equilibrium is locally asymptotically stable when [Formula: see text], while global stability is achieved when [Formula: see text]. To enhance disease management, we develop an optimal control strategy incorporating four time-dependent interventions. This comprehensive approach not only deepens our understanding of COVID-19 dynamics but also provides actionable insights for public health interventions aimed at controlling the spread of the virus.

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Publication Details

Journal
International Journal of Biomathematics
Published
2025-03-14
DOI
https://doi.org/10.1142/s1793524525500214
Primary Topic
COVID-19 epidemiological studies
Type
article
Field-Weighted Citation Impact
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article

Modeling the impact of quarantine on COVID-19 transmission: A comprehensive approach

Zohreh Eskandari, Nemat Nyamoradi, Fatemeh Sahami Nejhad
International Journal of Biomathematics
COVID-19 epidemiological studies
article

Modeling the impact of quarantine on COVID-19 transmission: A comprehensive approach

Zohreh Eskandari, Nemat Nyamoradi, Fatemeh Sahami Nejhad
article en

Abstract

The COVID-19 pandemic has had a profound global impact, necessitating an in-depth understanding of its transmission dynamics. This study presents a dynamic compartmental model that categorizes the population into six compartments: Susceptible (S), Exposed (E), Asymptomatic (A), Symptomatic (I), Quarantine (Q), and Recovered (R). We conduct a thorough analysis of the model, including the computation of the basic reproduction number [Formula: see text] and an examination of equilibrium points and bifurcation behaviors. Our findings indicate that the disease-free equilibrium is locally asymptotically stable when [Formula: see text], while global stability is achieved when [Formula: see text]. To enhance disease management, we develop an optimal control strategy incorporating four time-dependent interventions. This comprehensive approach not only deepens our understanding of COVID-19 dynamics but also provides actionable insights for public health interventions aimed at controlling the spread of the virus.

International Journal of Biomathematics
Razi University (IR), Fasa University of Medical Sciences (IR), Fasa University
Openalex Percentile: Top 94%
COVID-19 epidemiological studies
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