Case series of the first five human infections with monkeypox virus clade Ib and report on the public health response, United Kingdom, October to November 2024
We report two importations of monkeypox virus clade Ib infection to the United Kingdom in 2024. The first was a traveller returning from Tanzania, Rwanda and Uganda, the second from Uganda. Both presented with fever and typical skin lesions; 147 contacts were followed up, 19 vaccinated with MVA-BN. Three household contacts of the first individual, including two children, became infected. These are the first reported autochthonous transmissions of clade Ib in Europe, and first paediatric cases outside the African continent.
Authors
- Elizabeth Whittaker (ORCID: https://orcid.org/0000-0002-7944-8793)
- Brendan Payne (ORCID: https://orcid.org/0000-0002-3101-3512)
- Sherine Thomas
- Tommy Rampling (ORCID: https://orcid.org/0000-0001-9111-2486)
- Geraldine O’Hara (ORCID: https://orcid.org/0000-0002-1922-9492)
- Ellen Heinsbroek (ORCID: https://orcid.org/0000-0002-2874-6280)
- Susan Hopkins (ORCID: https://orcid.org/0000-0001-5179-5702)
- Merav Kliner
- William Welfare (ORCID: https://orcid.org/0000-0002-8304-1048)
- Gareth J Hughes (ORCID: https://orcid.org/0000-0002-3781-0117)
- Steven T. Pullan (ORCID: https://orcid.org/0000-0002-8983-599X)
- Natalie Groves (ORCID: https://orcid.org/0000-0002-3832-3484)
- Meera Chand (ORCID: https://orcid.org/0000-0001-9697-0340)
- Eileen Gallagher (ORCID: https://orcid.org/0009-0007-9223-5542)
- Jake Dunning (ORCID: https://orcid.org/0000-0002-4035-4562)
- Hannah E Emmett (ORCID: https://orcid.org/0000-0001-5105-9238)
- Amy Belfield (ORCID: https://orcid.org/0000-0001-8292-5506)
- Alejandra Alonso
- Simon Padfield
- N Claire Gordon (ORCID: https://orcid.org/0000-0001-8266-3630)
- Catherine Houlihan (ORCID: https://orcid.org/0000-0002-7539-1566)
- Muhammad Nadeem Alvi (ORCID: https://orcid.org/0000-0002-2625-9374)
- Mike Beadsworth
- Anne Tunbridge
- G. R. Armstrong
Institutions
- University College London Hospitals NHS Foundation Trust (GB)
- University of Liverpool (GB)
- Imperial College Healthcare NHS Trust (GB)
- Royal Free London NHS Foundation Trust (GB)
- Guy's and St Thomas' NHS Foundation Trust (GB)
- Newcastle upon Tyne Hospitals NHS Foundation Trust (GB)
- National Institute for Health and Care Research (GB)
- Sheffield Teaching Hospitals NHS Foundation Trust (GB)
- Evelina London Children's Healthcare (GB)
- Liverpool Womens NHS Foundation Trust (GB)
- University College London (GB)
Publication Details
- Journal
- Eurosurveillance
- Published
- 2025-03-13
- DOI
- https://doi.org/10.2807/1560-7917.es.2025.30.10.2500131
- Citations
- 5
- Primary Topic
- Poxvirus research and outbreaks
- Type
- article
- Field-Weighted Citation Impact
- 5.18