Refractory Vasospasm Presenting as Acute Myocardial Infarction

Refractory coronary artery spasm is a challenging condition with many complications, including acute myocardial infarction. We present the case of an elderly woman who developed refractory coronary artery vasospasm requiring extensive hemodynamic support. She had an abnormal electrocardiogram. She was diagnosed with severe coronary artery vasospasm that initially responded to intracoronary nitroglycerin. However, the course was complicated by arrhythmias and cardiogenic shock following an additional episode of vasospasm that required higher concentrations of nitroglycerin. Notably, this case is relatively less documented in women and within the South Bronx population. Refractory coronary artery spasm is a critical condition that can lead to life-threatening outcomes. Prompt and effective treatment is essential, especially for high-risk patients, to prevent cardiac ischemia. Given the significant dangers of delayed or insufficient treatment, it is crucial to manage coronary artery spasms proactively to enhance patient outcomes and avoid severe complications. In addition, this diagnosis should be strongly considered in women, with an emphasis on following guidelines for managing cases of acute myocardial infarction.

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Journal
Journal of Investigative Medicine High Impact Case Reports
Published
2025-03-14
DOI
https://doi.org/10.1177/23247096251325426
Primary Topic
Cardiac Imaging and Diagnostics
Type
article
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article

Refractory Vasospasm Presenting as Acute Myocardial Infarction

Ankita Gore, Nisha Ali, Nassim Krim, Nismat Javed et al.
1 links
Journal of Investigative Medicine High Impact Case Reports
Cardiac Imaging and Diagnostics
article

Refractory Vasospasm Presenting as Acute Myocardial Infarction

Ankita Gore, Nisha Ali, Nassim Krim, Nismat Javed, Maulin Patel, Emamuzo Otobo, Preeti Jadhav, Amandeep Singh
article en

Abstract

Refractory coronary artery spasm is a challenging condition with many complications, including acute myocardial infarction. We present the case of an elderly woman who developed refractory coronary artery vasospasm requiring extensive hemodynamic support. She had an abnormal electrocardiogram. She was diagnosed with severe coronary artery vasospasm that initially responded to intracoronary nitroglycerin. However, the course was complicated by arrhythmias and cardiogenic shock following an additional episode of vasospasm that required higher concentrations of nitroglycerin. Notably, this case is relatively less documented in women and within the South Bronx population. Refractory coronary artery spasm is a critical condition that can lead to life-threatening outcomes. Prompt and effective treatment is essential, especially for high-risk patients, to prevent cardiac ischemia. Given the significant dangers of delayed or insufficient treatment, it is crucial to manage coronary artery spasms proactively to enhance patient outcomes and avoid severe complications. In addition, this diagnosis should be strongly considered in women, with an emphasis on following guidelines for managing cases of acute myocardial infarction.

Journal of Investigative Medicine High Impact Case ReportsVol. 13
Icahn School of Medicine at Mount Sinai (US)
Good health and well-being
Openalex Percentile: Top 93%
Cardiac Imaging and Diagnostics
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Refractory Vasospasm Presenting as Acute Myocardial Infarction — Ankita Gore, Nisha Ali, et al. · Journal of Investigative Medicine High Impact Case Reports (2025) | TGRS Research Map | TGRS