Case-Based Review of Breast Imaging Changes Associated With GLP-1 Agonists

Abstract Purpose of Review This article will review several cases demonstrating breast imaging findings following the use of glucagon-like peptide-1 (GLP-1) agonists, including the relevant implications in changing breast density and supplemental screening. Recent Findings GLP-1 agonists may be associated with breast changes and symptoms that warrant further breast imaging, including supplemental screening and/or for problem solving in the appropriate clinical scenario. Summary Breast imaging findings following the use of GLP-1 agonists may vary, including both significant and insignificant increases in breast density. Patients with increased breast density may warrant further evaluation with supplemental screening. Following the use of GLP-1 agonists, patients may also present with symptoms warranting further targeted imaging evaluation. Knowledge of the spectrum of breast changes associated with GLP-1 agonists is necessary to adequately assess the need for supplemental screening and/or additional targeted breast imaging.

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Publication Details

Journal
Current Radiology Reports
Published
2025-03-14
DOI
https://doi.org/10.1007/s40134-025-00433-2
Primary Topic
Diabetes Treatment and Management
Type
article
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article

Case-Based Review of Breast Imaging Changes Associated With GLP-1 Agonists

Joseph Villavicencio, Samantha P. Zuckerman
Current Radiology Reports
Diabetes Treatment and Management
article

Case-Based Review of Breast Imaging Changes Associated With GLP-1 Agonists

Joseph Villavicencio, Samantha P. Zuckerman
article en

Abstract

Abstract Purpose of Review This article will review several cases demonstrating breast imaging findings following the use of glucagon-like peptide-1 (GLP-1) agonists, including the relevant implications in changing breast density and supplemental screening. Recent Findings GLP-1 agonists may be associated with breast changes and symptoms that warrant further breast imaging, including supplemental screening and/or for problem solving in the appropriate clinical scenario. Summary Breast imaging findings following the use of GLP-1 agonists may vary, including both significant and insignificant increases in breast density. Patients with increased breast density may warrant further evaluation with supplemental screening. Following the use of GLP-1 agonists, patients may also present with symptoms warranting further targeted imaging evaluation. Knowledge of the spectrum of breast changes associated with GLP-1 agonists is necessary to adequately assess the need for supplemental screening and/or additional targeted breast imaging.

Current Radiology ReportsVol. 13(1)
University of Miami (US), Hospital of the University of Pennsylvania (US), Sylvester Comprehensive Cancer Center (US)
Openalex Percentile: Top 93%
Diabetes Treatment and Management
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Case-Based Review of Breast Imaging Changes Associated With GLP-1 Agonists — Joseph Villavicencio, Samantha P. Zuckerman · Current Radiology Reports (2025) | TGRS Research Map | TGRS