The Role of Contact Allergens on Facial Seborrheic Dermatitis

BACKGROUND/AIMS: Seborrheic dermatitis (SD) is an inflammatory skin condition characterised by scaly erythematous patches. The causes of SD include inflammatory reaction to Malassezia species, genetic predisposition and hormonal factors; however, any association with contact allergens has not been established. The purpose of this study is to investigate the role of contact allergens on facial SD. MATERIALS AND METHODS: Thirty patients with symptoms of, or a prediagnosis of, facial SD along with 30 healthy individuals as the control group were included in this study. Two different sets of patch tests (international standard series IS-1000 and cosmetic series C-1000) were used in this study. Allergens were placed in small chambers and applied to the patients’ backs. They were then evaluated 48 hours, 72 hours, and 1 week after the patches were removed. The results were classified according to the International Contact Dermatitis Research Group. RESULTS: Positive reactions to standard and cosmetic series patch test allergens in the patient and control groups were not statistically significant. CONCLUSION: It is not possible to establish an association between contact allergens and facial SD.

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Publication Details

Journal
Cyprus Journal of Medical Sciences
Published
2025-03-14
DOI
https://doi.org/10.4274/cjms.2024.2024-54
Primary Topic
Nail Diseases and Treatments
Type
article
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article

The Role of Contact Allergens on Facial Seborrheic Dermatitis

İçim Kömürcügil, Nermin Karaosmanoğlu, Gülfem Ünsal
Cyprus Journal of Medical Sciences
Nail Diseases and Treatments
article

The Role of Contact Allergens on Facial Seborrheic Dermatitis

İçim Kömürcügil, Nermin Karaosmanoğlu, Gülfem Ünsal
article en

Abstract

BACKGROUND/AIMS: Seborrheic dermatitis (SD) is an inflammatory skin condition characterised by scaly erythematous patches. The causes of SD include inflammatory reaction to Malassezia species, genetic predisposition and hormonal factors; however, any association with contact allergens has not been established. The purpose of this study is to investigate the role of contact allergens on facial SD. MATERIALS AND METHODS: Thirty patients with symptoms of, or a prediagnosis of, facial SD along with 30 healthy individuals as the control group were included in this study. Two different sets of patch tests (international standard series IS-1000 and cosmetic series C-1000) were used in this study. Allergens were placed in small chambers and applied to the patients’ backs. They were then evaluated 48 hours, 72 hours, and 1 week after the patches were removed. The results were classified according to the International Contact Dermatitis Research Group. RESULTS: Positive reactions to standard and cosmetic series patch test allergens in the patient and control groups were not statistically significant. CONCLUSION: It is not possible to establish an association between contact allergens and facial SD.

Cyprus Journal of Medical SciencesVol. 10(1)
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Nail Diseases and Treatments
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The Role of Contact Allergens on Facial Seborrheic Dermatitis — İçim Kömürcügil, Nermin Karaosmanoğlu, et al. · Cyprus Journal of Medical Sciences (2025) | TGRS Research Map | TGRS