Integrating DNA and RNA sequencing for enhanced pathogen detection in respiratory infections
This research established the robust performance of our tailored tNGS assay in the simultaneous detection of DNA and RNA pathogens, underscoring its prospective suitability for widespread use in clinical diagnostics.
Authors
- Yuxing Chu (ORCID: https://orcid.org/0000-0001-9331-5914)
- Jun She (ORCID: https://orcid.org/0000-0001-5318-0197)
- Binghuai Lu (ORCID: https://orcid.org/0000-0003-3510-2747)
- Rui Gao (ORCID: https://orcid.org/0000-0003-0021-3527)
- Jie Liu (ORCID: https://orcid.org/0000-0002-9792-5127)
- Dejian Gu
- Jiaping Wang (ORCID: https://orcid.org/0000-0001-9022-0231)
- Yuting Yi (ORCID: https://orcid.org/0000-0003-2125-9073)
- Hao Liu (ORCID: https://orcid.org/0000-0002-2366-9554)
Institutions
- Fudan University (CN)
- China-Japan Friendship Hospital (CN)
- Zhongshan Hospital (CN)
- Annoroad Gene Technology (China) (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-03-14
- DOI
- https://doi.org/10.1186/s12967-025-06342-4
- Citations
- 11
- Primary Topic
- Pneumonia and Respiratory Infections
- Type
- article
- Field-Weighted Citation Impact
- 14.90
Funders
- Alpha Foundation for the Improvement of Mine Safety and Health