<i>Candida albicans</i> : A Comprehensive View of the Proteome

We describe a new release of the <i>Candida albicans</i> PeptideAtlas proteomics spectral resource (build 2024-03), providing a sequence coverage of 79.5% at the canonical protein level, matched mass spectrometry spectra, and experimental evidence identifying 3382 and 536 phosphorylated serine and threonine sites with false localization rates of 1% and 5.3%, respectively. We provide a tutorial on how to use the PeptideAtlas and associated tools to access this information. The <i>C. albicans</i> PeptideAtlas summary web page provides "Build overview", "PTM coverage", "Experiment contribution", and "Data set contribution" information. The protein and peptide information can also be accessed via the <i>Candida</i> Genome Database via hyperlinks on each protein page. This allows users to peruse identified peptides, protein coverage, post-translational modifications (PTMs), and experiments that identify each protein. Given the value of understanding the PTM landscape in the sequence of each protein, a more detailed explanation of how to interpret and analyze PTM results is provided in the PeptideAtlas of this important pathogen. <i>Candida albicans</i> PeptideAtlas web page: https://db.systemsbiology.net/sbeams/cgi/PeptideAtlas/buildDetails?atlas_build_id=578.

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Publication Details

Journal
Journal of Proteome Research
Published
2025-03-14
DOI
https://doi.org/10.1021/acs.jproteome.4c01020
Citations
1
Primary Topic
Antifungal resistance and susceptibility
Type
article
Field-Weighted Citation Impact
1.40

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article

Candida albicans : A Comprehensive View of the Proteome

Gloria Molero, Concha Gil, Lucía Monteoliva, Robert L. Moritz et al.
1 citations
Journal of Proteome Research
Antifungal resistance and susceptibility
1.40
article

Candida albicans : A Comprehensive View of the Proteome

Gloria Molero, Concha Gil, Lucía Monteoliva, Robert L. Moritz, Eric W. Deutsch, Ana Borrajo, Zhi Sun, Aída Pitarch, Samuel de la Cámara Fuentes, María Luisa Hernáez, Leticia Gomez-Artiguez
article en
1 citations

Abstract

We describe a new release of the <i>Candida albicans</i> PeptideAtlas proteomics spectral resource (build 2024-03), providing a sequence coverage of 79.5% at the canonical protein level, matched mass spectrometry spectra, and experimental evidence identifying 3382 and 536 phosphorylated serine and threonine sites with false localization rates of 1% and 5.3%, respectively. We provide a tutorial on how to use the PeptideAtlas and associated tools to access this information. The <i>C. albicans</i> PeptideAtlas summary web page provides "Build overview", "PTM coverage", "Experiment contribution", and "Data set contribution" information. The protein and peptide information can also be accessed via the <i>Candida</i> Genome Database via hyperlinks on each protein page. This allows users to peruse identified peptides, protein coverage, post-translational modifications (PTMs), and experiments that identify each protein. Given the value of understanding the PTM landscape in the sequence of each protein, a more detailed explanation of how to interpret and analyze PTM results is provided in the PeptideAtlas of this important pathogen. <i>Candida albicans</i> PeptideAtlas web page: https://db.systemsbiology.net/sbeams/cgi/PeptideAtlas/buildDetails?atlas_build_id=578.

Journal of Proteome ResearchVol. 24(4)
Universidad Complutense de Madrid (ES), North Seattle College (US), Institute for Systems Biology (US), Abterra Biosciences (United States) (US)
National Science Foundation, Comunidad de Madrid, Ministerio de Ciencia, Tecnología e Innovación Productiva, National Institutes of Health, Agencia Estatal de Investigación
Zero hunger
Openalex Percentile: Top 23%
Antifungal resistance and susceptibility
1.40
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