Long-term CSF responses in adult patients with spinal muscular atrophy type 2 or 3 on treatment with nusinersen
The present multi-proteomic analysis contributes to the understanding of the molecular mechanisms underlying nusinersen's therapeutic effects and offers potential biomarkers for monitoring treatment response in SMA.
Authors
- Brigitte Wildemann (ORCID: https://orcid.org/0000-0002-5389-3338)
- Gina Cebulla
- Dirk C. Hoffmann (ORCID: https://orcid.org/0000-0003-1370-1933)
- Markus Weiler (ORCID: https://orcid.org/0000-0002-8942-7662)
- Mirjam Korporal‐Kuhnke (ORCID: https://orcid.org/0000-0001-8070-7142)
- Wolfgang Wick (ORCID: https://orcid.org/0000-0002-6171-634X)
- Uwe Warnken (ORCID: https://orcid.org/0000-0001-9337-1879)
- Ling Hai (ORCID: https://orcid.org/0000-0001-8719-2727)
- Tobias Keßler (ORCID: https://orcid.org/0000-0001-8350-7074)
- Cansu Güngör (ORCID: https://orcid.org/0009-0002-4405-1427)
Institutions
- German Cancer Research Center (DE)
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
- National Center for Tumor Diseases (DE)
Publication Details
- Journal
- Journal of Neurology
- Published
- 2025-03-14
- DOI
- https://doi.org/10.1007/s00415-025-12984-7
- Citations
- 4
- Primary Topic
- Neurogenetic and Muscular Disorders Research
- Type
- article
- Field-Weighted Citation Impact
- 6.50
Funders
- Deutsches Krebsforschungszentrum
- Bundesministerium für Bildung und Forschung
- Universitätsklinikum Heidelberg