Alternate encoder and dual decoder CNN-Transformer networks for medical image segmentation

Accurately extracting lesions from medical images is a fundamental but challenging problem in medical image analysis. In recent years, methods based on convolutional neural networks and Transformer have achieved great success in the medical image segmentation field. Combining the powerful perception of local information by CNNs and the efficient capture of global context by Transformer is crucial for medical image segmentation. However, the unique characteristics of many lesion tissues often lead to poor performance and most previous models failed to fully extract effective local and global features. Therefore, based on an encoder-decoder architecture, we propose a novel alternate encoder dual decoder CNN-Transformer network, AD2Former, with two attractive designs: 1) We propose alternating learning encoder can achieve real-time interaction between local and global information, allowing both to mutually guide learning. 2) We propose dual decoder architecture. The unique way of dual-branch independent decoding and fusion. To efficiently fuse different feature information from two sub-decoders during decoding, we introduce a channel attention module to reduce redundant feature information. Driven by these two designs, AD2Former demonstrates strong capture ability for target regions and fuzzy boundaries. Experiments on multi-organ segmentation and skin lesion segmentation datasets also demonstrate the effectiveness and superiority of AD2Former.

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Publication Details

Journal
Scientific Reports
Published
2025-03-14
DOI
https://doi.org/10.1038/s41598-025-93353-2
Citations
14
Primary Topic
Brain Tumor Detection and Classification
Type
article
Field-Weighted Citation Impact
11.79
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article

Alternate encoder and dual decoder CNN-Transformer networks for medical image segmentation

Lin Zhang, Weigang Wang, Xinyu Guo, Liwei Yao et al.
14 citations
Scientific Reports
Brain Tumor Detection and Classification
11.79
article

Alternate encoder and dual decoder CNN-Transformer networks for medical image segmentation

Lin Zhang, Weigang Wang, Xinyu Guo, Liwei Yao, Hongkun Sun
article en
14 citations

Abstract

Accurately extracting lesions from medical images is a fundamental but challenging problem in medical image analysis. In recent years, methods based on convolutional neural networks and Transformer have achieved great success in the medical image segmentation field. Combining the powerful perception of local information by CNNs and the efficient capture of global context by Transformer is crucial for medical image segmentation. However, the unique characteristics of many lesion tissues often lead to poor performance and most previous models failed to fully extract effective local and global features. Therefore, based on an encoder-decoder architecture, we propose a novel alternate encoder dual decoder CNN-Transformer network, AD2Former, with two attractive designs: 1) We propose alternating learning encoder can achieve real-time interaction between local and global information, allowing both to mutually guide learning. 2) We propose dual decoder architecture. The unique way of dual-branch independent decoding and fusion. To efficiently fuse different feature information from two sub-decoders during decoding, we introduce a channel attention module to reduce redundant feature information. Driven by these two designs, AD2Former demonstrates strong capture ability for target regions and fuzzy boundaries. Experiments on multi-organ segmentation and skin lesion segmentation datasets also demonstrate the effectiveness and superiority of AD2Former.

Scientific ReportsVol. 15(1)
Zhejiang Hospital (CN), Zhejiang Gongshang University (CN)
Openalex Percentile: Top 1%
Brain Tumor Detection and Classification
11.79
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Alternate encoder and dual decoder CNN-Transformer networks for medical image segmentation — Lin Zhang, Weigang Wang, et al. · Scientific Reports (2025) | TGRS Research Map | TGRS