Combination therapy with Chicoric acid and PD-1/PD-L1 blockade improves the immunotherapy response in patient-derived ovarian cancer xenograft model
This study demonstrated that combination therapy with CA and aPD-1/aPD-L1 might be a promising strategy for treating OC effectively.
Authors
- Helei Hou (ORCID: https://orcid.org/0000-0001-8502-7461)
- Xingfa Huo (ORCID: https://orcid.org/0000-0002-7302-464X)
- Hongwei Lan
- Yuming Zhang (ORCID: https://orcid.org/0000-0002-0057-2936)
- Chuantao Zhang (ORCID: https://orcid.org/0000-0003-1212-971X)
- Xiaochun Zhang (ORCID: https://orcid.org/0000-0003-3271-7260)
- Na Zhou (ORCID: https://orcid.org/0000-0001-9488-4713)
- Fangfang Yang (ORCID: https://orcid.org/0000-0002-9803-1096)
- Jingjuan Zhu
Institutions
- Qingdao University (CN)
- Affiliated Hospital of Qingdao University (CN)
Publication Details
- Journal
- Cell Communication and Signaling
- Published
- 2025-03-14
- DOI
- https://doi.org/10.1186/s12964-025-02146-7
- Citations
- 1
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 1.05
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Shandong Province