LONG-NEXT: A new accurate and efficient NGS-based method for GBA1 analysis in Parkinson disease
LONG-NEXT is a reliable, fast, cost-effective alternative for GBA1 sequencing and may prove strategic in light of current genotype-based tailored therapies specifically targeting GBA1-PD patients.
Authors
- Patrizia Dentelli
- Ettore Zapparoli (ORCID: https://orcid.org/0000-0003-4170-7902)
- Marco J. Morelli (ORCID: https://orcid.org/0000-0003-1862-667X)
- Anna Scarabotto
- Serena Pagliarani (ORCID: https://orcid.org/0000-0002-7145-1998)
- Tiziana Martone
- Barbara Pasini (ORCID: https://orcid.org/0000-0002-4373-1212)
- Marco Percetti (ORCID: https://orcid.org/0000-0003-4679-3360)
- Danara Ormanbekova (ORCID: https://orcid.org/0000-0002-6564-3109)
- Paola Mandich (ORCID: https://orcid.org/0000-0003-3123-3512)
- Andrea Gaudio (ORCID: https://orcid.org/0000-0002-3377-3953)
- Edoardo Monfrini (ORCID: https://orcid.org/0000-0003-4720-9234)
- Lucia Trevisan (ORCID: https://orcid.org/0000-0002-8608-4342)
- Raffaella Minardi (ORCID: https://orcid.org/0000-0002-8190-8517)
- Paola Origone
- Alessia Fiorentino (ORCID: https://orcid.org/0000-0002-1403-4581)
- Enza Maria Valente (ORCID: https://orcid.org/0000-0002-0600-6820)
- Silvia Marino (ORCID: https://orcid.org/0000-0002-1088-6808)
- Valério Carelli (ORCID: https://orcid.org/0000-0003-4923-6404)
- Ilaria Palmieri (ORCID: https://orcid.org/0000-0002-0304-7299)
- Claudia Ledda (ORCID: https://orcid.org/0000-0003-0839-932X)
- Chiara Sorbera (ORCID: https://orcid.org/0000-0002-5872-3119)
- Micol Avenali (ORCID: https://orcid.org/0000-0002-7880-9921)
- Giada Cuconato
- Alessio Di Fonzo
- Sara Tenace
Institutions
- University of Milan (IT)
- University of Pavia (IT)
- Foundation Center (US)
- Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT)
- Azienda Ospedaliera Citta' della Salute e della Scienza di Torino (IT)
- Ospedale Maggiore (IT)
- Fondazione Istituto Neurologico Nazionale Casimiro Mondino (IT)
- Istituto delle Scienze Neurologiche di Bologna (IT)
- Ospedale Policlinico San Martino (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Ferrari (Italy) (IT)
- Centro Neurolesi Bonino Pulejo (IT)
- Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele (IT)
- University of Turin (IT)
Publication Details
- Journal
- Parkinsonism & Related Disorders
- Published
- 2025-03-14
- DOI
- https://doi.org/10.1016/j.parkreldis.2025.107780
- Citations
- 4
- Primary Topic
- Lysosomal Storage Disorders Research
- Type
- article
- Field-Weighted Citation Impact
- 4.66
Funders
- Ministero della Salute