AYURVEDIC UNDERSTANDING OF THE ETIOPATHOGENESIS OF DIABETICPERIPHERAL NEUROPATHY

Introduction: One of the most common consequences of diabetes is diabetic neuropathy, which is frequently underdiagnosed and undertreated. Neuropathy affects approximately 50% of individuals with diabetes. Diabetes mellitus shares similarities with Madhumeha in terms of etiopathogenesis and symptomatology. In Avaranjanya Madhumeha vitiated Pitta, Meda and Kapha lead to the Avarana of Vata, exacerbating the condition and hinder-ing the formation of essential Dhatus, resulting in complications such as diabetic peripheral neuropathy. Diabetic neuropathies are believed to arise from diabetic microvascular injury affecting the small blood vessels that sup-ply nerves, in addition to macrovascular conditions that may culminate in diabetic neuropathy. Despite signifi-cant advancements in insulin and hypoglycemic medications that have benefited people with diabetes, these pa-tients still lack adequate treatment for their neuropathic complications. Diminished perception of vibration and impairment of other modalities of sensation are the most typical indications of diabetic sensory polyneuropathy. Materials and Method: A review of various classical textbooks, journals and modern literature supporting the understanding of diabetic peripheral neuropathy (DPN) was conducted. Discussion: Symptoms of diabetic pe-ripheral neuropathy can be identified by characteristics such as Karapadadaha (burning sensation), Cumcuma-yana (tingling sensation) and Suptata (numbness) which are observed in Madhumeha at any stage during the dis-ease's Purvarupa (prodromal), Rupa (sign and symptom) or Upadrava (complication) stages. Conclusion: A review of diabetic peripheral neuropathy based on the etiopathology and symptoms of DPN in Ayurveda re-vealed its similarities with Madhumeha Purvarupa, Lakshana and Upadrava.