Zebrafish and cellular models of SELENON-Congenital myopathy exhibit novel embryonic and metabolic phenotypes
These data demonstrate a role for SelN in zebrafish early development and myoblast metabolism and provide a basis for cellular and animal model assays for SELENON-CM.
Authors
- Behzad Moghadaszadeh (ORCID: https://orcid.org/0000-0001-9787-0106)
- Pamela Barraza‐Flores (ORCID: https://orcid.org/0000-0001-9468-5757)
- Piotr Sliz (ORCID: https://orcid.org/0000-0002-6522-0835)
- Emily Hickey (ORCID: https://orcid.org/0000-0002-9526-4468)
- Alan H. Beggs (ORCID: https://orcid.org/0000-0001-8818-0568)
- Shira Rockowitz (ORCID: https://orcid.org/0000-0003-1490-592X)
- Biju Isaac
- Liang Sun (ORCID: https://orcid.org/0000-0002-0321-9222)
- Won Lee (ORCID: https://orcid.org/0000-0002-6383-8754)
Institutions
- Boston Children's Hospital (US)
- Harvard University (US)
- Dana-Farber/Boston Children's Cancer and Blood Disorders Center (US)
Publication Details
- Journal
- Skeletal Muscle
- Published
- 2025-03-15
- DOI
- https://doi.org/10.1186/s13395-025-00376-4
- Citations
- 5
- Primary Topic
- Muscle Physiology and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 4.03
Funders
- Muscular Dystrophy Association
- National Institute of Neurological Disorders and Stroke
- Eunice Kennedy Shriver National Institute of Child Health and Human Development